Abstract | UNLABELLED: BACKGROUND: PATIENTS: 22 cyanotic patients with a oxygen saturation of 82% (38-92%), age 14 years (5-42 years) and six controls with atrial septal defect, age 37 years (28-66 years) were investigated with repeated urinary analyses. RESULTS: Before operation, six of 22 of the cyanotic patients had albuminuria. Postoperatively three patients developed acute renal failure including glomerular and tubular damage. Urinary albumin analysis >1000 mg g(-1) creatinine after 24 h and N-acteyl-beta-D- glucosaminidase analysis >100 U g(-1) creatinine after 48 h predicted dialysis requirement. In noncyanotic controls only one preoperative and none of the postoperative analyses were pathological. CONCLUSIONS:
|
Authors | S Dittrich, K Kurschat, I Dähnert, M Vogel, C Müller, V Alexi-Meskishvili, P E Lange |
Journal | International journal of cardiology
(Int J Cardiol)
Vol. 73
Issue 2
Pg. 173-9
(Apr 28 2000)
ISSN: 0167-5273 [Print] Netherlands |
PMID | 10817857
(Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
|
Chemical References |
- Creatinine
- Acetylglucosaminidase
|
Topics |
- Acetylglucosaminidase
(urine)
- Acute Kidney Injury
(etiology, prevention & control, urine)
- Adolescent
- Adult
- Aged
- Albuminuria
(etiology)
- Cardiopulmonary Bypass
(adverse effects)
- Child
- Child, Preschool
- Creatinine
(urine)
- Cyanosis
(etiology)
- Heart Defects, Congenital
(complications, surgery)
- Heart Septal Defects, Atrial
(surgery)
- Humans
- Kidney Function Tests
- Middle Aged
- Postoperative Complications
(prevention & control, urine)
- Predictive Value of Tests
- Proteinuria
(etiology)
- Risk Factors
|