Use of a dry latex agglutination test to measure eradication of Helicobacter pylori infection.

Abstract

BACKGROUND AND METHODS:

A total antibody latex serology test was compared with enzyme immunoassay serology after treatment for Helicobacter pylori infection in 22 patients.

RESULTS:

Nineteen patients were cured of infection, but only nine (47%) were negative by the latex test after 6 months. However a significant decline in immunoglobulin (Ig)G was seen in 90% of the cured patients.

CONCLUSIONS:

Although the latex test is suitable for initial diagnosis of H. pylori infection, it is not suitable for monitoring treatment success. A decline in IgG of more than 40% correlates well with successful eradication of H. pylori.

• Authors: P D Midolo, B Dakic, L Nicholson, J R Lambert, S Lin, E G Russell
• Journal: Journal of gastroenterology and hepatology (J Gastroenterol Hepatol) Vol. 15 Issue 3 Pg. 254-6 (Mar 2000) ISSN: 0815-9319 [Print] Australia
• PMID: 10764024 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Bacterial Agents
• Antibodies, Bacterial
• Immunoglobulin A
• Immunoglobulin G

Topics

• Anti-Bacterial Agents (therapeutic use)
• Antibodies, Bacterial (analysis)
• Helicobacter Infections (diagnosis, drug therapy, microbiology)
• Helicobacter pylori (immunology)
• Humans
• Immunoenzyme Techniques
• Immunoglobulin A (immunology)
• Immunoglobulin G (immunology)
• Latex Fixation Tests (methods)
• Remission Induction
• Sensitivity and Specificity