Tumor-associated glycoprotein 72 (TAG-72) expression in salivary gland neoplasia: an immunohistochemical study using the monoclonal antibody (MAb) CC49.
Abstract | OBJECTIVES: The purpose of this study was to investigate immunohistochemically the expression of tumor-associated glycoprotein 72 (TAG-72) using the monoclonal antibody (MAb) CC49 in salivary gland neoplasia and normal salivary glands in an attempt to determine the potential usefulness of MAb CC49 in diagnostic and therapeutic applications. MATERIALS AND METHODS: RESULTS: CONCLUSIONS: Our results suggest the potential use of MAb CC49 in the differential diagnosis of some salivary gland neoplasms in which their histopathologic features overlap, and in the radiation immunolocalization and immunotherapy of malignant tumors that are localized in the parotid gland.
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Authors | A Epivatianos, A Poulopoulos, I Kayavis, P Papanayotou |
Journal | Oral diseases
(Oral Dis)
Vol. 6
Issue 2
Pg. 112-7
(Mar 2000)
ISSN: 1354-523X [Print] Denmark |
PMID | 10702789
(Publication Type: Journal Article)
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Chemical References |
- Antibodies, Monoclonal
- Antibodies, Neoplasm
- Antigens, Neoplasm
- B72.3 antibody
- Biomarkers, Tumor
- Coloring Agents
- Fluorescent Dyes
- Glycoproteins
- tumor-associated antigen 72
- Eosine Yellowish-(YS)
- Hematoxylin
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Topics |
- Adenocarcinoma
(genetics, pathology)
- Antibodies, Monoclonal
- Antibodies, Neoplasm
- Antigens, Neoplasm
(analysis, genetics)
- Biomarkers, Tumor
(analysis, genetics)
- Carcinoma
(genetics, pathology)
- Carcinoma, Adenoid Cystic
(genetics, pathology)
- Carcinoma, Mucoepidermoid
(genetics, pathology)
- Coloring Agents
- Cystadenocarcinoma, Papillary
(genetics, pathology)
- Eosine Yellowish-(YS)
- Fluorescent Dyes
- Gene Expression Regulation, Neoplastic
- Glycoproteins
(analysis, genetics)
- Hematoxylin
- Humans
- Immunoenzyme Techniques
- Immunohistochemistry
- Parotid Gland
(cytology, metabolism)
- Retrospective Studies
- Salivary Gland Neoplasms
(genetics, pathology)
- Salivary Glands
(cytology, metabolism)
- Salivary Glands, Minor
(cytology, metabolism)
- Sublingual Gland
(cytology, metabolism)
- Submandibular Gland
(cytology, metabolism)
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