[Artificial amniotic fluid instillation in premature rupture of fetal membranes and extreme prematurity as alternative therapy].

Abstract

We report two cases of premature rupture of membranes and oligohydramnios (gestational age: 23rd/24th week). In both pregnancies artificial instillation of amniotic fluid (AIF) was performed once a week. We hypothesize that fetal head compression with impaired cerebral perfusion due to oligohydramnios causes periventricular leukomalacia. Prolongation of gestation of 36/23 days without neurological lesion support this method. Surveillance of these pregnancies in a perinatal center has to include very early detection of chorioamnionitis. If not so, gained prolongation of pregnancy with a lower rate of cerebral damage becomes harmful due to infection. Clinical benefits and disadvantages of this technique have to be evaluated in a prospective randomized trial.

• Authors: R Faber, E Robel-Tillig, C Vogtmann, H Stepan, B Viehweg
• Journal: Zeitschrift fur Geburtshilfe und Neonatologie (Z Geburtshilfe Neonatol) 1999 Jul-Aug Vol. 203 Issue 4 Pg. 170-2 ISSN: 0948-2393 [Print] Germany
• Vernacular Title: Artifizielle Fruchtwasser-Instillation bei vorzeitigem Blasensprung und extremer Unreife als alternative Therapie.
• PMID: 10483700 (Publication Type: Case Reports, Journal Article)

Topics

• Amniotic Fluid
• Female
• Fetal Membranes, Premature Rupture (diagnostic imaging, therapy)
• Humans
• Infant, Newborn
• Infant, Very Low Birth Weight
• Instillation, Drug
• Obstetric Labor, Premature (diagnostic imaging, therapy)
• Oligohydramnios (diagnostic imaging, therapy)
• Pregnancy
• Pregnancy Trimester, Second
• Ultrasonography, Prenatal