Experimental intraspinal trypanosoma equiperdum infection in a horse.

Abstract

To establish the ability of Trypanosoma equiperdum to cross the blood-brain-barrier in the horse, a susceptible stallion was infected via the cerebrospinal fluid of the subarachnoid space by lumbosacral puncture. Cerebrospinal fluid with low detectable levels of trypanosomes removed from a dourine-infected mare by lumbosacral puncture was used for infecting the animal. The parasite was detected in blood smears of the recipient 13 days after infection and the subsequent parasitaemia and clinical course of the disease followed that of naturally infected horses.

• Authors: P R Barrowman
• Journal: The Onderstepoort journal of veterinary research (Onderstepoort J Vet Res) Vol. 43 Issue 4 Pg. 201-2 (Dec 1976) ISSN: 0030-2465 [Print] South Africa
• PMID: 1023092 (Publication Type: Journal Article)

Topics

• Animals
• Blood (parasitology)
• Blood-Brain Barrier
• Cerebrospinal Fluid (parasitology)
• Female
• Horse Diseases (parasitology)
• Horses
• Male
• Trypanosoma (isolation & purification)
• Trypanosomiasis (parasitology, veterinary)