Zuclomiphene (Zuclomifene)

The cis or (Z)-isomer of clomiphene.

Also Known As:

Zuclomifene; (Z)-2-(p-(2-Chloro-1,2-Diphenylvinyl)phenoxy)triethylamine; (Z)-2-(p-(2-Chloro-1,2-Diphenylvinyl)phenoxy)triethylamine Citrate; Zuclomifene Citrate; Citrate, Zuclomifene

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        Clomiphene: 2111
        Zuclomiphene: 6

Experts

1.	Ellen, Joseph: 1 article (01/2017)
2.	Feustel, Paul: 1 article (01/2017)
3.	Fontenot, Gregory: 1 article (01/2017)
4.	Helo, Sevann: 1 article (01/2017)
5.	Hsu, Kuang: 1 article (01/2017)
6.	Mahon, Joseph: 1 article (01/2017)
7.	McCullough, Andrew: 1 article (01/2017)
8.	Welliver, Charles: 1 article (01/2017)
9.	Wiehle, Ron: 1 article (01/2017)
10.	Ghobadi, Cyrus: 1 article (02/2009)

Related Diseases

1.	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 02/01/2009 - "The pharmacokinetics of the zuclomiphene (Zu) and enclomiphene (En) isomers of clomiphene citrate following a single oral dose (50 mg) were characterized for the first time in patients receiving the drug (ie, infertile women with polycystic ovary syndrome). "
2.	Neoplasms (Cancer) 09/01/1998 - "However, CLO is a mixture of two stereoisomers, enclomiphene (ENC) and zuclomiphene (ZUC), which have distinctly different activities on reproductive tissues and tumor cells. "
3.	Hypogonadism (Hypergonadotropic Hypogonadism) 01/01/2017 - "Serum levels of enclomiphene and zuclomiphene in men with hypogonadism on long-term clomiphene citrate treatment." 01/01/2017 - "To determine the relative concentrations of enclomiphene (ENC) and zuclomiphene (ZUC) isomers in men with hypogonadism on long-term clomiphene citrate (CC) therapy, and to determine whether patient age, body mass index (BMI) or duration of therapy were predictive of relative concentrations of ENC and ZUC. "
4.	Hypertrophy 02/01/1984 - "Five daily injections of enclomiphene, zuclomiphene, tamoxifen, nafoxidine, CI 628 or CI 680 (500 micrograms per injection) promote uterine luminal epithelial cell hypertrophy characteristic of exogenous estrogen administration. "
5.	Breast Neoplasms (Breast Cancer) 08/01/1983 - "The antitumor activity of three enclomiphene (trans-1- (p-beta-diethylaminoethoxyphenyl)1,2-diphenyl-2-chloroethylene) analogs and the cis isomer zuclomiphene was investigated in MCF 7 human mammary carcinoma cells in culture. "

Related Drugs and Biologics

1.	Enclomiphene (Enclomifene)
2.	Clomiphene (Clomifene)
3.	Triparanol
4.	Tamoxifen
5.	Phenobarbital (Luminal)
6.	Nitromifene
7.	Nafoxidine
8.	Estrogens (Estrogen)
9.	trans- 1,4- Bis(2- chlorobenzaminomethyl)cyclohexane Dihydrochloride
10.	3- (p- (alpha- (p- methoxyphenyl)beta- nitrostyryl)phenoxy)- N,N- dimethylpropylamine monocitrate

Related Therapies and Procedures

1.	Therapeutics
2.	Injections
3.	Duration of Therapy