Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways.
Also Known As:
ARHGEF1; Cool-1 Protein; PAK-Interacting Exchange Factor beta; Rho Guanine Nucleotide Exchange Factor (GEF) 1; Rho Guanine Nucleotide Exchange Factor 6; Rho Guanine Nucleotide Exchange Factor 7; Rho Guanine Nucleotide Exchange Factor p115; RhoGEF; beta PIX Protein; betaPIX Protein; p115 RhoGEF; p115RhoGEF; Cool 1 Protein; PAK Interacting Exchange Factor beta; PIX Protein, beta; Protein, Cool-1; Protein, beta PIX; Protein, betaPIX; RhoGEF, p115