S100 Calcium Binding Protein G

A calbindin protein found in many mammalian tissues, including the UTERUS, PLACENTA, BONE, PITUITARY GLAND, and KIDNEYS. In intestinal ENTEROCYTES it mediates intracellular calcium transport from apical to basolateral membranes via calcium binding at two EF-HAND MOTIFS. Expression is regulated in some tissues by VITAMIN D.

Also Known As:

Calbindin 3; Calbindin D9K; Calbindin-D9K; Calcium Binding Protein, Vitamin D Dependent; Calcium-Binding Protein, Vitamin D-Dependent; Cholecalcin; IMCal Protein; Intestinal Membrane Calcium-Binding Protein; Vitamin D-Dependent Calcium-Binding Protein; Intestinal Membrane Calcium Binding Protein; Vitamin D Dependent Calcium Binding Protein

Networked: 32 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Calcium-Binding Proteins: 1333
      - S100 Proteins: 3806
        S100 Calcium Binding Protein G: 32
        human S100G protein
        mouse S100g protein
        rat S100g protein
      - Calbindins: 376
        S100 Calcium Binding Protein G: 32
        human S100G protein
        mouse S100g protein
        rat S100g protein

Experts

1.	Ahn, Changhwan: 1 article (05/2020)
2.	Hong, Eui-Ju: 1 article (05/2020)
3.	Jeon, Bo-Hui: 1 article (05/2020)
4.	Jeung, Eui-Bae: 1 article (05/2020)
5.	Jung, Eui-Man: 1 article (05/2020)
6.	Kim, Woo-Yang: 1 article (05/2020)
7.	Park, Seon Young: 1 article (05/2020)
8.	Yoo, Yeong-Min: 1 article (05/2020)
9.	Fan, Gaoyang: 1 article (01/2020)
10.	Han, Hao: 1 article (01/2020)

Related Diseases

1.	Uremia 02/01/1996 - "A single injection of 1,25-(OH)2D3 to uremic rats caused an increase in the steady-state calbindin-D9k mRNA level, and decreases in steady state c-fos and ODC mRNA levels, suggesting that the deficiency of 1,25-(OH)2D3 is responsible for intestinal dysfunction in uremia. " 11/16/1992 - "In contrast, chronic uremia increased renal calbindin-D28K by 51% and 38% (P < 0.001) in placebo and MP treated uremic rats, respectively, while intestinal calbindin-D9K was unchanged. " 02/01/1996 - "Calcium absorption and gene expression of calbindin-D9k were decreased in uremia and were also improved by phosphorus restriction. "
2.	Leiomyoma (Uterine Fibroids) 06/01/1996 - "This study describes the properties of a myometrial cell line, m-M116, that was derived from a leiomyoma developed in an adult female transgenic mouse harboring the simian virus 40 large T antigen (Tag) under the control of the 5'-regulatory sequence of the calbindin D9k (CaBP9k) gene. "
3.	Body Weight (Weight, Body) 01/01/1992 - "Dexamethasone treatment (50 micrograms.100 g body weight-1.d-1 for 4 d) results in a 75% decrease in rat intestinal calbindin-D9k mRNA. " 01/01/1986 - "Betamethasone (50 micrograms/kg body weight/day) given to young pigs reduced calcium absorption, growth and plasma vitamin D dependent calcium binding protein (CaBP) concentration. " 10/15/1989 - "Vitamin D-deficient rats responded to dexamethasone treatment (100 micrograms/100 g of body weight/day for 4 days) with a 2.5-fold increase in intestinal VDR mRNA which was accompanied by a 4-fold decrease in intestinal calbindin-D9k mRNA. " 05/01/1991 - "The deficiencies of calbindin-D9k and alkaline phosphatase could not be attributed to malnutrition or to a generalized brush-border defect as indicated by body weights and the intestinal marker enzyme sucrase. "
4.	Hypertension (High Blood Pressure) 09/01/1991 - "Abnormal intestinal regulation of calbindin-D9K and calmodulin by dietary calcium in genetic hypertension." 01/01/1994 - "The effects of calcitriol and a novel calcitriol analogue, 22-oxacalcitriol (OCT) on duodenal Ca transport, calbindin-D9k mRNA, and calbindin-D9k content were studied in two animal models reflecting common human pathologies, namely arterial hypertension and chronic renal failure, as well as in normal rats. " 08/01/1994 - "Induction of hypertension in Dahl-S rats reduced intestinal calbindin-D9k and increased plasma levels of 1,25(OH)2 vitamin D, while renal calbindin-D28k levels, plasma calcium levels and plasma magnesium levels were unchanged. "
5.	Ganglion Cysts (Ganglion) 01/29/1986 - "Vestibular sensory hair cells, afferent fibres and vestibular ganglion neurones of the cat are intensely labelled by a specific antibody to rat kidney vitamin D-dependent calcium-binding protein (CaBP-28K). " 01/29/1986 - "Immunocytochemical detection of vitamin D-dependent calcium-binding protein (CaBP-28K) in vestibular sensory hair cells and vestibular ganglion neurones of the cat." 05/01/2015 - "Recently, calretinin, a vitamin D-dependent calcium-binding protein with expression in ganglion cells and nerves, has been described as an adjunctive or primary diagnostic test in HD. "

Related Drugs and Biologics

1.	Calcium
2.	Phosphorus (Red Phosphorus)
3.	Tumor Viral Antigens (Large T Antigen)
4.	Messenger RNA (mRNA)
5.	Calbindin 1
6.	Vitamin D
7.	Calcitriol (Calcijex)
8.	Calbindins
9.	Estrogens (Estrogen)
10.	Dexamethasone (Maxidex)