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Dandruff

Excessive shedding of dry scaly material from the scalp in humans.
Also Known As:
Scurf
Networked: 331 relevant articles (35 outcomes, 63 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Seborrheic Dermatitis
2. Dermatitis
3. Psoriasis (Pustulosis Palmaris et Plantaris)
4. Skin Diseases (Skin Disease)
5. Pruritus (Itching)

Experts

1. Supuran, Claudiu T: 13 articles (12/2020 - 04/2012)
2. Capasso, Clemente: 11 articles (12/2020 - 11/2015)
3. Del Prete, Sonia: 9 articles (01/2020 - 11/2015)
4. Vullo, Daniela: 8 articles (05/2019 - 04/2012)
5. Jung, Won Hee: 7 articles (12/2020 - 03/2017)
6. Park, Minji: 7 articles (12/2020 - 03/2017)
7. Clavaud, Cécile: 6 articles (05/2022 - 01/2016)
8. Lee, Yang Won: 6 articles (12/2020 - 03/2017)
9. Dawson, Thomas L: 5 articles (02/2021 - 12/2005)
10. Cho, Yong-Joon: 5 articles (01/2020 - 03/2017)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Dandruff:
1. pyrithione zinc (ZPT)FDA Link
2. Ketoconazole (Nizoral)FDA LinkGeneric
3. SilverIBA
4. selenium disulfide (Head & Shoulders)FDA LinkGeneric
5. Ciclopirox (Loprox)FDA LinkGeneric
6. Antifungal AgentsIBA
7. climbazoleIBA
8. piroctone olamineIBA
9. SolutionsIBA
10. Fatty Acids (Saturated Fatty Acids)IBA
02/01/1986 - "Abundance of hair fat on the scalp after puberty, colonization by fat-splitting micro-organisms (notably yeasts of the genus Pityrosporum) and transitory upsurges of epidermal mitosis in response to fatty acids produced by lipolysis of sebum triglycerides within the hair follicles, especially those in the anagen phase, seem likely to be implicated in the generation of dandruff scaling. "
05/01/2014 - "In this study, the authors investigated the efficacy of a moisturising leave-on lotion (LOL) containing a high concentration of glycerol (10%) and other known skin benefit agents (saturated fatty acid and sunflower seed oil) to reduce dandruff over an 8-week treatment period with 3 applications per week. "
06/01/2023 - "The formulations are mainly intended for use in nonspecific areas of skin (29), eye areas (12), scalp hair (9) and lip skin (2) with claims of anti-ageing, moisturizers, sun protection, hair growth, anti-dandruff, etc. CONCLUSION: Coffee and its residues have high amounts of phenolic compounds, caffeine, fatty acids and other substances known to have important biological properties for the skin. "
12/01/2011 - "The current hypothesis is that dandruff and SD are linked to fatty acid metabolism and secretory lipolytic enzymes, which hydrolyse sebaceous lipids and release irritating free fatty acids. "
07/01/2002 - "In both populations, dandruff was associated with a dramatic decrease in free lipid levels, with significant decreases in ceramides, fatty acids, and cholesterol. "

Therapies and Procedures

1. Therapeutics
2. Aftercare (After-Treatment)
03/01/2023 - "SeS2 is beneficial in scalp dandruff, even after treatment interruption. "
08/01/2014 - "Understanding the dandruff scalp before and after treatment: an in vivo Raman spectroscopic study."
06/01/2011 - "Shampoo 1 showed a significantly higher anti-mycotics substantivity compared to shampoo 2. After treatment with shampoo 1, the wet combing force was significantly reduced compared with shampoo 2, suggesting a better combability following the use of shampoo 1. In an in vivo split head design study, shampoo 1 was shown to be equally effective in reducing the amount of dandruff on the scalp compared with shampoo 2. The approval rate of volunteers regarding the question 'The use of this shampoo decreases the itching of my scalp?' after a 4-week treatment with shampoo 1 equaled 90%. "
05/01/2022 - "Selenium disulfide provides an additional benefit on the scalp microbiota and in clinical symptoms of SD and dandruff after treatment with ketoconazole. "
04/01/2017 - "Limited data exists regarding evidence-based treatment for CCCA.</p> <p>OBJECTIVE: To examine photos of subjects with CCCA before and after treatment in order to evaluate results of treatment and compare results of different treatment regimens.</p> <p>METHODS: Photographs of 15 subjects with CCCA before and after treatment were evaluated by two blinded investigators who assigned disease severity scores to photographs based on a published scale: Central Scalp Alopecia Photographic Scale in African American Women.</p> <p>RESUTLS: Median change in severity score (post-treatment severity score - pre-treatment severity score) was 0.5 (P = 0.58) for all 15 subjects receiving a series of 7 to 8 intralesional steroid injections along with topical steroids (Class I/II) +/- minoxidil and +/- anti-dandruff shampoo, indicating worsening of disease after treatment. "
3. Unani Medicine
4. Hair Removal (Depilation)
5. Duration of Therapy