N-Terminal Acetyltransferase B

An N-terminal acetyltransferase subtype that consists of the Naa20p catalytic subunit and the Naa25p auxiliary subunit. The structure of this enzyme is conserved between YEASTS and HUMAN. It has specificity for the N-terminal METHIONINE of peptides where the next amino acid in the chain is either ASPARTATE; GLUTAMATE; ASPARAGINE; or GLUTAMINE.

Also Known As:

N-Terminal Acetyltransferase Type B; NatB N-Terminal Acetyltransferase; N Terminal Acetyltransferase B; N Terminal Acetyltransferase Type B; N-Terminal Acetyltransferase, NatB; NatB N Terminal Acetyltransferase

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Acyltransferases: 374
      - Acetyltransferases: 1040
        N-Terminal Acetyltransferases: 17
        N-Terminal Acetyltransferase B: 1
        human NAA20 protein
        human NAA25 protein
        mouse Naa20 protein
        mouse Naa25 protein
        S cerevisiae MAK10 protein
        S cerevisiae MDM20 protein
        S cerevisiae Nat3 protein

Experts

1.	Jang, Mi-Mi: 1 article (11/2020)
2.	Jin, Gyu-Rin: 1 article (11/2020)
3.	Ju, Bong-Gun: 1 article (11/2020)
4.	Jung, Taek-Yeol: 1 article (11/2020)
5.	Kim, Chan-Woo: 1 article (11/2020)
6.	Kim, EungHan: 1 article (11/2020)
7.	Kim, Hyelee: 1 article (11/2020)
8.	Kim, Hyun-Seok: 1 article (11/2020)
9.	Kim, TaeSoo: 1 article (11/2020)
10.	Kim, Wankyu: 1 article (11/2020)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 11/01/2020 - "N-α-acetyltransferase 20 (Naa20), which is a catalytic subunit of the N-terminal acetyltransferase B (NatB) complex, has recently been reported to be implicated in hepatocellular carcinoma (HCC) progression and autophagy, but the underlying mechanism remains unclear. "

Related Drugs and Biologics

1.	Acetyltransferases