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Chloroacetates

ACETIC ACID or acetic acid esters substituted with one or more CHLORINE atoms.

Also Known As:

Chloroacetic Acids; Acids, Chloroacetic

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Chlorinated Hydrocarbons: 240
      - Chloroacetates: 3
        Trichloroacetic Acid: 456
        Dichloroacetic Acid: 164
        mitaplatin: 3
        trichloroacetamide: 3
        diammine(dichloroacetato)platinum(II): 1
        2-methyl-4-nitroanilinium trichloroacetate trichloroacetic acid
        ethyl trichloroacetate
        methyl trichloroacetate
        N,N-dimethyltrichloroacetamide
        N-chloroacetyl parafuchsin
        tetramethylammonium hydrogen bis(trichloroacetate)
        trichloroacetic anhydride
        trichloroacetyl chloride
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - Chloroacetates: 3
        Trichloroacetic Acid: 456
        Dichloroacetic Acid: 164
        mitaplatin: 3
        trichloroacetamide: 3
        diammine(dichloroacetato)platinum(II): 1
        2-methyl-4-nitroanilinium trichloroacetate trichloroacetic acid
        ethyl trichloroacetate
        methyl trichloroacetate
        N,N-dimethyltrichloroacetamide
        N-chloroacetyl parafuchsin
        tetramethylammonium hydrogen bis(trichloroacetate)
        trichloroacetic anhydride
        trichloroacetyl chloride

Related Diseases

1.

Neoplasms (Cancer)

01/01/1992 - "These studies provide further evidence that the chloroacetic acids lack genotoxic activity not only in rodent liver, a tissue in that they induce tumors, but in a variety of other roden tissues and cultured cell types.(ABSTRACT TRUNCATED AT 400 WORDS)"
09/01/1997 - "The results also suggest some potential growth signal transduction pathways that may contribute to the DCA promotion of tumors, further support the premise that these two chloroacetates promote hepatocarcinogenesis in different ways, and provide a rational basis for a similar comparison with TCE. "
04/19/1996 - "Both chloroacetic acids promoted MNU-initiated foci and tumors, however their concentration-response relationships differed being exponential and linear for DCA or TCA, respectively. "