Percutaneous Coronary Intervention

A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.

Also Known As:

Percutaneous Coronary Revascularization; Coronary Intervention, Percutaneous; Coronary Interventions, Percutaneous; Coronary Revascularization, Percutaneous; Coronary Revascularizations, Percutaneous; Intervention, Percutaneous Coronary; Interventions, Percutaneous Coronary; Percutaneous Coronary Interventions; Percutaneous Coronary Revascularizations; Revascularization, Percutaneous Coronary; Revascularizations, Percutaneous Coronary

Networked: 23796 relevant articles (1145 outcomes, 4770 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 34913
- Minimally Invasive Surgical Procedures: 4949
  - Endovascular Procedures: 3003
    - Percutaneous Coronary Intervention: 23796
      - Coronary Atherectomy
      - Coronary Balloon Angioplasty
- Cardiovascular Surgical Procedures: 39
  - Vascular Surgical Procedures: 4113
    - Endovascular Procedures: 3003
      - Percutaneous Coronary Intervention: 23796
        Coronary Atherectomy
        Coronary Balloon Angioplasty

Experts

1.	Stone, Gregg W: 436 articles (10/2022 - 01/2002)
2.	Mehran, Roxana: 419 articles (11/2022 - 01/2002)
3.	Jeong, Myung Ho: 240 articles (07/2022 - 03/2003)
4.	Serruys, Patrick W: 230 articles (01/2022 - 01/2003)
5.	Bhatt, Deepak L: 188 articles (12/2022 - 01/2002)
6.	Valgimigli, Marco: 168 articles (11/2022 - 03/2005)
7.	Windecker, Stephan: 162 articles (11/2022 - 05/2005)
8.	Kastrati, Adnan: 159 articles (10/2022 - 01/2002)
9.	Waksman, Ron: 157 articles (10/2022 - 01/2002)
10.	Dudek, Dariusz: 154 articles (09/2022 - 01/2002)

Related Diseases

1.	ST Elevation Myocardial Infarction 06/30/2017 - "The best treatment approach for ST-segment elevation myocardial infarction (STEMI) is prompt primary percutaneous coronary intervention (PCI). " 12/30/2016 - "CONCLUSIONS Although the most appropriate timing to treat simultaneous multiple culprit lesions has yet to be definitively defined, multi-vessel percutaneous coronary intervention in the setting of a STEMI with multiple culprit lesions is feasible with good outcome as shown by our index case." 12/01/2016 - "Primary percutaneous coronary intervention is the most effective treatment for patients with ST-segment elevation myocardial infarction (STEMI). " 03/18/2014 - "Treatment times for ST-elevation myocardial infarction (STEMI) patients presenting to percutaneous coronary intervention hospitals have improved dramatically over the past 10 years, particularly for patients using emergency medical services. " 06/01/2013 - "Primary percutaneous coronary intervention is the best treatment of patients with ST elevation myocardial infarction (STEMI). "
2.	Myocardial Infarction 01/01/2014 - "Reperfusion by means of percutaneous coronary intervention or thrombolytic therapy is the most effective treatment for acute myocardial infarction, markedly reducing mortality and morbidity. " 12/01/2004 - "A short course of cardiac rehabilitation program is highly cost effective in improving long-term quality of life in patients with recent myocardial infarction or percutaneous coronary intervention." 11/01/2016 - "Recent advances in percutaneous coronary intervention and antiplatelet therapy as well as faster door-to-balloon times have markedly improved the therapy of patients with acute myocardial infarction. " 01/01/2009 - "Scientific evidence shows fibrinolysis to be effective in aborting myocardial infarction, but for percutaneous coronary intervention this has not been proven. " 05/01/2008 - "Achievement of the angiographic gold standard TIMI 3 flow (Thrombolysis in Myocardial Infarction) flow grade during PCI (percutaneous coronary intervention) in the setting of AMI (acute myocardial infarction) is insufficient for attainment of optimal prognostic benefit, as there is a poor prognosis for patients with evidence of inadequate flow at the tissue level despite patent coronary arteries. "
3.	Acute Coronary Syndrome 01/01/2021 - "Percutaneous coronary intervention (PCI) is one of the most effective treatments for acute coronary syndrome (ACS). " 01/01/2015 - "Percutaneous coronary intervention (PCI) is known as the most effective treatment for acute coronary syndrome (ACS). " 01/01/2018 - "Although the percutaneous coronary intervention (PCI) has proven to be effective in decreasing mortality rates among patients with acute coronary syndromes, the previous meta-analyses of PCI versus optimal medical therapy for stable CAD have not been able to demonstrate a reduction in major adverse cardiac outcomes. " 02/01/2016 - "Percutaneous coronary intervention (PCI) is safe and effective in very elderly patients, defined as those who are age ≥85 years, with acute coronary syndrome (ACS). " 12/01/2013 - "Pharmacotherapies with agents that inhibit platelet function have proven to be effective in the treatment of acute coronary syndromes, and in the prevention of complications during and after percutaneous coronary intervention. "
4.	Coronary Artery Disease (Coronary Atherosclerosis) 07/25/2017 - "Current 2nd-generation drug-eluting stents (DES) have dramatically improved clinical outcomes after percutaneous coronary intervention for coronary artery disease. " 03/01/2014 - "Percutaneous coronary intervention (PCI) is a highly effective treatment for obstructive coronary artery disease. " 11/01/2013 - "Although patients aged 65 years or more have been referred to surgical or percutaneous coronary interventions, the best option for coronary artery disease treatment remains uncertain. " 10/01/2022 - "Compare the safety and efficacy of BVS versus DES in patients receiving percutaneous coronary intervention for coronary artery disease across a complete range of randomised controlled trial (RCT) follow-up intervals. " 05/01/2011 - "The COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation) trial was designed to compare optimal medical therapy alone versus optimal medical therapy and percutaneous coronary intervention (PCI) for treatment of patients with stable coronary artery disease and showed equal efficacy for optimal medical therapy with or without PCI. "
5.	Thrombosis (Thrombus) 05/01/2016 - "Although drug-eluting stents (DES) for percutaneous coronary intervention (PCI) have dramatically reduced the incidence of in-stent restenosis, their deployment for large-size coronary lesions is still controversial because of problems such as late in-stent thrombosis and late catch-up in DES. " 02/01/2011 - "Despite improved stent implantation technologies and effective antiplatelet regimens, stent thrombosis has been one of the most important problem in percutaneous coronary intervention. " 01/01/2014 - "Although DESs have incrementally improved outcomes after percutaneous coronary intervention, delayed re-endothelialization and stent thrombosis remain important challenges. " 02/01/2001 - "These data suggest that thrombus debulking prior to percutaneous transluminal coronary intervention by therapeutic ultrasound is a very safe and effective percutaneous coronary intervention strategy. " 07/01/2011 - "Despite significant benefits including mortality advantage demonstrated with antiplatelet therapy in large clinical trials, the occurrence of adverse ischemic events, including stent thrombosis after percutaneous coronary intervention has been the challenging and devastating complication. "

Related Drugs and Biologics

1.	Clopidogrel (Plavix)
2.	Aspirin (Acetylsalicylic Acid)
3.	bivalirudin (Angiomax)
4.	Glycoproteins (Glycoprotein)
5.	Prasugrel Hydrochloride
6.	Heparin (Liquaemin)
7.	Ticagrelor
8.	Platelet Membrane Glycoprotein IIb
9.	Abciximab (ReoPro)
10.	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))

Related Therapies and Procedures

1.	Therapeutics
2.	Stents
3.	Coronary Artery Bypass (Coronary Artery Bypass Surgery)
4.	Drug-Eluting Stents
5.	Thrombolytic Therapy