NAV1.6 Voltage-Gated Sodium Channel

A voltage-gated sodium channel subtype found widely expressed in neurons of the central and peripheral nervous systems. Defects in the SCN8A gene which codes for the alpha subunit of this sodium channel are associated with ATAXIA and cognitive deficits.

Also Known As:

SCN8A Sodium Channel alpha Subunit; Type 8 Voltage-Gated Sodium Channel; Voltage-Gated Sodium Channel Type 8; NAV1.6 Voltage Gated Sodium Channel; Type 8 Voltage Gated Sodium Channel; Voltage Gated Sodium Channel Type 8; Voltage Gated Sodium Channel Type 8 Subunit alpha; Voltage-Gated Sodium Channel Type 8 Subunit alpha

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843

Experts

1.	Bhatia, Kailash P: 1 article (01/2017)
2.	Erro, Roberto: 1 article (01/2017)
3.	Espay, Alberto J: 1 article (01/2017)
4.	Striano, Pasquale: 1 article (01/2017)

Related Diseases

1.	Channelopathies 01/01/2017 - "Here, we review the clinical and pathophysiological aspects of the paroxysmal dyskinesias, further proposing a pathophysiological framework according to which they can be classified as synaptopathies (proline-rich transmembrane protein 2 and myofibrillogenesis regulator gene), channelopathies (calcium-activated potassium channel subunit alpha-1 and voltage-gated sodium channel type 8), or transportopathies (solute carrier family 2 member 1). "
2.	Chorea (Rheumatic Chorea) 01/01/2017 - "Here, we review the clinical and pathophysiological aspects of the paroxysmal dyskinesias, further proposing a pathophysiological framework according to which they can be classified as synaptopathies (proline-rich transmembrane protein 2 and myofibrillogenesis regulator gene), channelopathies (calcium-activated potassium channel subunit alpha-1 and voltage-gated sodium channel type 8), or transportopathies (solute carrier family 2 member 1). "

Related Drugs and Biologics

1.	Calcium-Activated Potassium Channels (Calcium-Activated Potassium Channel)
2.	human PRRT2 protein