A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of SKELETAL MYOCYTES. Defects in the SCN4A gene, which codes for the alpha subunit of this sodium channel, are associated with several MYOTONIC DISORDERS.
Also Known As:
NAV1.4 alpha Subunit; SCN4A Sodium Channel alpha Subunit; Sodium Channel, Voltage-Gated, Type IV, alpha 1 Subunit; Type 4 Voltage-Gated Sodium Channel; Voltage-Gated Sodium Channel Type 4; NAV1.4 Voltage Gated Sodium Channel; Subunit, NAV1.4 alpha; Type 4 Voltage Gated Sodium Channel; Voltage Gated Sodium Channel Type 4; Voltage Gated Sodium Channel Type 4 Subunit alpha; alpha Subunit, NAV1.4; Voltage-Gated Sodium Channel Type 4 Subunit alpha