An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.
Also Known As:
B7-H1 Immune Costimulatory Protein; B7H1 Immune Costimulatory Protein; CD274 Antigen; PD-L1 Costimulatory Protein; Programmed Cell Death 1 Ligand 1; Antigen, B7-H1; Antigen, CD274; B7 H1 Antigen; B7 H1 Immune Costimulatory Protein; CD274 Antigens; Costimulatory Protein, PD-L1; PD L1 Costimulatory Protein; PD L1 Protein; Antigens, CD274; PD-L1 Protein; Programmed Cell Death 1 Ligand 1 Protein; Programmed Death Ligand 1