Argonaute Proteins

A family of RNA-binding proteins that has specificity for MICRORNAS and SMALL INTERFERING RNA molecules. The proteins take part in RNA processing events as core components of RNA-induced silencing complex.

Also Known As:

Ago Subfamily of Argonaute Proteins; PIWI Subfamily of Argonaute Proteins; Protein, Argonaute; Proteins, Argonaute; Ago Subfamily of Argonaute Protein; Argonaute Protein; PIWI Subfamily of Argonaute Protein

Networked: 32 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Konkimalla, V Badireenath: 2 articles (09/2016 - 06/2015)
2.	Rath, Surya Narayan: 2 articles (09/2016 - 06/2015)
3.	Nowak, Iwona: 1 article (02/2021)
4.	Sarshad, Aishe A: 1 article (02/2021)
5.	Halushka, Marc K: 1 article (01/2021)
6.	Karakousis, Petros C: 1 article (01/2021)
7.	Looney, Monika M: 1 article (01/2021)
8.	Lu, Yin: 1 article (01/2021)
9.	Teng, Yao: 1 article (01/2021)
10.	Wang, Yajun: 1 article (01/2021)

Related Diseases

1.	Neoplasms (Cancer) 02/13/2021 - "Argonaute Proteins Take Center Stage in Cancers." 05/01/2020 - "Association between genetic variants in genes encoding Argonaute proteins and cancer risk: A meta-analysis." 01/01/2019 - "The highly conserved Argonaute protein family members play a central role in the regulation of gene expression networks, orchestrating the establishment and the maintenance of cell identity throughout the entire life cycle, as well as in several human disorders, including cancers. " 01/01/2013 - "Expression of the Argonaute proteins were assessed by immunohistochemistry (IHC) in tissue microarrays (TMA), containing paired tumor tissue and adjacent non-cancer tissue from 176 patients who had undergone surgery in hospital for histologically proven ccRCC. " 02/10/2010 - "Argonaute proteins are overexpressed in colon cancer relative to adjacent non-cancer tissue. "
2.	Carcinogenesis 01/01/2013 - "In summary, our present study clarify that the aberrant expression of Argonaute in human RCC is possibly involved with tumorigenesis and development, and the Argonaute protein could act as a potential biomarker for prognosis assessment of renal cancer. "
3.	Virus Diseases (Viral Diseases) 01/01/2012 - "Previous studies highlighted different roles of the 20S proteasome in plant defense during virus infection, either indirectly through viral suppressor-mediated degradation of Argonaute proteins, affecting the RNA interference pathway, or directly through modulation of the proteolytic and RNase activity of the 20S proteasome, a component of the 20S proteasome, by viral proteins, affecting the levels of viral proteins and RNAs. "
4.	Kidney Neoplasms (Kidney Cancer) 01/01/2013 - "In summary, our present study clarify that the aberrant expression of Argonaute in human RCC is possibly involved with tumorigenesis and development, and the Argonaute protein could act as a potential biomarker for prognosis assessment of renal cancer. "
5.	Infections 01/01/2022 - "Small RNAs, in association with Argonaute proteins, tune the expression of genes participating in nodule development and rhizobial infection. " 03/01/2015 - "Roles and programming of Arabidopsis ARGONAUTE proteins during Turnip mosaic virus infection." 04/10/2012 - "In fibroblasts, RhCMV miRNAs associate with Argonaute proteins and display several patterns of expression, including an early peak in expression followed by decline and accumulation throughout infection. " 06/01/2019 - "Of these common DEGs, the changes in expression of argonaute proteins, thioredoxins and peroxidases showed that the activation of RNA silencing and the destruction of redox balance can be induced by tobacco mosaic virus infection, resulting in the reset of biology process and damage in tobacco plants. "

Related Drugs and Biologics

1.	MicroRNAs (MicroRNA)
2.	Biomarkers (Surrogate Marker)
3.	Proteasome Endopeptidase Complex (Proteasome)
4.	Ribonucleases (Ribonuclease)
5.	Viral Proteins
6.	Proteins (Proteins, Gene)
7.	RNA (Ribonucleic Acid)
8.	Piwi-Interacting RNA
9.	Long Noncoding RNA
10.	Core Binding Factors (Core-Binding Factor)