Tetraspanin 25

A tetraspanin protein found at high levels in cells of the lymphoid-myeloid lineage. It may function in regulating the differentiation of T-LYMPHOCYTES and the activation of B-LYMPHOCYTES.

Also Known As:

CD53 Antigen; Tetraspanin-25; Antigen, CD53; CD53 Antigens; Antigens, CD53

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Tetraspanins: 761
      - Tetraspanin 25: 4
        human CD53 protein
        mouse Cd53 protein
        rat Cd53 protein

Experts

1.	Lazo, Pedro A: 1 article (02/2003)
2.	Yunta, Mónica: 1 article (02/2003)

Related Diseases

1.	Neoplasms (Cancer) 02/27/2003 - "The CD53 antigen interactions might contribute to cell survival in poorly vascularized regions of the tumor mass." 02/27/2003 - "We have studied the effect of CD53 antigen ligation on the survival response of tumor cells to serum deprivation, a well-known stimulator of cell death that may mimic the tumor environment; for this aim IR938F and Jurkat cells, a B- and T-cell lymphoma, were used. " 01/01/1993 - "Although various cell surface antigens were detectable in SRBCS, the pan-leukocytic-histiocytic CD53 antigen was absent in the neoplastic population of all tumors studied; this finding allowed the authors to discriminate these lesions from lymphomas and leukemias. "
2.	T-Cell Lymphoma (Lymphoma, T Cell) 02/27/2003 - "We have studied the effect of CD53 antigen ligation on the survival response of tumor cells to serum deprivation, a well-known stimulator of cell death that may mimic the tumor environment; for this aim IR938F and Jurkat cells, a B- and T-cell lymphoma, were used. "
3.	B-Cell Lymphoma (Lymphoma, B Cell) 04/10/1996 - "CD53 antigen and epidermal growth factor induce similar changes in the pattern of phorbol ester binding in a B cell lymphoma."
4.	Lymphoma (Lymphomas) 01/01/1993 - "Although various cell surface antigens were detectable in SRBCS, the pan-leukocytic-histiocytic CD53 antigen was absent in the neoplastic population of all tumors studied; this finding allowed the authors to discriminate these lesions from lymphomas and leukemias. "
5.	Leukemia 01/01/1993 - "Although various cell surface antigens were detectable in SRBCS, the pan-leukocytic-histiocytic CD53 antigen was absent in the neoplastic population of all tumors studied; this finding allowed the authors to discriminate these lesions from lymphomas and leukemias. "

Related Drugs and Biologics

1.	Phorbol Esters
2.	Epidermal Growth Factor (EGF)
3.	Surface Antigens (Surface Antigen)

Related Therapies and Procedures

1.	Ligation