HLA-B37 Antigen

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*37 allele family.

Also Known As:

HLA B37; HLA Class I Histocompatibility Antigen, B-37 alpha Chain; HLA-B37; Antigen, HLA-B37; HLA B37 Antigen; HLA Class I Histocompatibility Antigen, B 37 alpha Chain

Networked: 8 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Boon, T: 1 article (11/2002)
2.	Russo, V: 1 article (11/2002)
3.	Stroobant, V: 1 article (11/2002)
4.	Zhang, Y: 1 article (11/2002)
5.	van der Bruggen, P: 1 article (11/2002)

Related Diseases

1.	Human Influenza (Influenza) 02/23/1989 - "These two peptides have previously been shown to act respectively as targets for certain HLA-A2 or HLA-B37 restricted influenza-specific cytotoxic T lymphocytes (CTL). " 09/01/1992 - "In addition, we have extended studies from our group that have evaluated the capacity of a similar panel of peptides to inhibit presentation of an influenza nucleoprotein peptide NP (335-349) by HLA-B37 and a matrix peptide, M1 (57-68), by HLA-A2 to the appropriate peptide-specific CTL lines. " 02/23/1989 - "Here we describe a gel filtration assay from which we derive direct evidence for selective binding of an influenza matrix peptide to HLA-A2 and for binding of an influenza nucleoprotein peptide to HLA-B37. " 10/01/1990 - "Studies on human anti-influenza cytolytic activities have demonstrated that cytotoxic T lymphocytes (CTL) from HLA-B37 individuals react preferentially with the peptide corresponding to residues 335-349 of the nucleoprotein, whereas CTL from HLA-A2 donors recognize peptide 57-68 from the viral matrix as a dominant epitope. "
2.	Mastocytoma 11/01/1991 - "Genomic cloning and expression of HLA-B37 in the mouse mastocytoma cell line P815-HTR."
3.	Gingival Overgrowth 07/01/1996 - "The data at present available would suggest that the severity of gingival overgrowth is also significantly associated with the HLA-B37 phenotype."
4.	B-Cell Lymphoma (Lymphoma, B Cell) 11/01/1982 - "Significant associations were observed between HLA-AW33 and Caucasoid B-cell lymphomas, and for HLA AW24, HLA-B37 and HLA-B40 and B cell lymphomas in Negroids. "
5.	Ankylosing Spondylitis 06/01/1977 - "In man, associations have been shown between the presence of Hodgkin's Disease and a number of cross-reacting HLA types (BW5, BW15, BW18), between systemic Lupus erythematosus and HLA type BW15 in Caucasians and BW35 in blacks, between HLA B37 and ankylosing spondylitis in Caucasians, between HLA B8 and gluten-sensitive enteropathy and between HLA B13 and psoriasis, a disease having a strong hereditary element. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	HLA-A2 Antigen (HLA A2 Antigen)
3.	Nucleoproteins
4.	Epitopes
5.	HLA-B40 Antigen
6.	HLA-B13 Antigen
7.	Elements
8.	HLA-A*33 antigen