Laxatives

04/01/2013 - "The actual knowledge on the efficacy and safety of currently available laxative treatment for chronic constipation, as shown by the review on which this editorial comments, clearly demonstrates that constipation may be effectively treated in most cases. "
02/01/1999 - "Laxative use is frequent in institutions for the mentally retarded, with a large inter-institution variation, indicating that constipation is an important problem and underlining the need for research into cost-effective treatment."
01/01/2022 - "Medicinal plants possess a significant laxative potential and support their folklore; therefore, further, well-designed clinical-based studies are required to prove and improve the efficacy of herbal medicine for constipation. "
11/05/2021 - "There was a significant improvement in constipation of elderly patients when probiotics were administered in combination with a laxative, suggesting that it may be a more effective treatment. "
05/01/2017 - "Symptoms of constipation improved to a greater degree and there was a significant reduction in laxative use in the Lepicol group."

04/01/1998 - "There was a significant reduction in need to strain, abdominal pain, bloating, and oral laxative use. "
01/01/2020 - "We compared improvement in FI, bowel movement (BM) frequency, abdominal pain, laxative use, and complications. "
09/01/2014 - "In addition, the number of bowel movements with straining decreased (p < 0.001) and stool form improved (p < 0.001), while days with laxative intake and days with abdominal pain decreased (p = 0.001 and p = 0.027, respectively). "
09/01/2003 - "Clinical manifestations including straining, abdominal pain, bloating, were relieved, and less oral laxative was used. "
01/01/1997 - "Fiber and bulk laxatives decreased abdominal pain and improved stool consistency compared with placebo. "

05/01/1997 - "Most children with fecal incontinence benefit from a strict treatment plan that includes defecation trials, a fiber-rich diet and laxative medications. "
04/01/2017 - "We compared ACE/laxative usage, PedsQL Gastrointestinal Symptom Scale (GSS), Fecal Incontinence Quality of Life Scale (FIQL), Fecal Incontinence Severity Index (FISI), and Vancouver Dysfunctional Elimination Syndrome Score (DES) at baseline and progressive follow-up time intervals. "
04/01/2016 - "Relapses, fecal incontinence, and laxative use were not different between interventions. "
04/01/2016 - "phone contacts, relapse, fecal incontinence, and laxative use. "
01/01/2016 - "Successful clinical outcomes were defined as ≥3 bowel movements weekly for ≥4 weeks, with ≤2 fecal incontinence episodes monthly, irrespective of laxative use. "

01/01/2006 - "Treatment with the laxative alone (Group A) resulted in significant increase in frequency of bowel movements (P < 0.05), but not significant improvement in pain (P > 0.05). "
09/18/2015 - "Laxative versus laxative plus bulking agentOnly one trial was included in this comparison and reported on pain or straining on defecation in women who underwent surgical repair of third degree perineal tears; there was no reported difference between groups (median (range) data only). "
01/01/2021 - "Efficacy endpoints included the proportion of patients achieving rescue-free laxation (RFL), time to RFL, weekly laxations within 24 hours after dosing, rescue laxative use, and pain scores. "
01/01/2021 - "Osmotic laxative use leads to earlier bowel movements and less pain during the first bowel movement. "
01/01/2019 - "At the 1-year follow-up, the patient had complaints about neither defecation nor pain, and no longer needed laxative agents. "

10/05/2018 - "The obtained results indicated that FCAE exhibits a natural laxative effect without provoking diarrhea and ameliorates functional gastrointestinal (GI) and motility disorders thus justifying its traditional usage."
01/01/2022 - "Three EHR-based interventions were sequentially implemented: (1) alert when ordering a CDT if laxatives administered within 24 hours (January 2018); (2) cancellation of CDT orders after 24 hours (October 2018); (3) contextual rule-driven order questions requiring justification when laxative administered or lack of EHR documentation of diarrhea (July 2019). "
01/01/2019 - "Diarrhea and laxative use were common and similarly distributed in those appropriately or inappropriately tested. "
04/01/2018 - "Reasons included testing in a patient without significant diarrhea or with recent laxative use, or delayed testing. "
01/01/2017 - "difficile testing of stools from patients without clinically significant diarrhea and in patients with recent laxative use."