A flavoprotein and iron sulfur-containing oxidoreductase complex that catalyzes the conversion of UBIQUINONE to ubiquinol. In MITOCHONDRIA the complex also couples its reaction to the transport of PROTONS across the internal mitochondrial membrane. The NADH DEHYDROGENASE component of the complex can be isolated and is listed as EC 1.6.99.3.
Also Known As:
NADH-CoQ Reductase; NADH Dehydrogenase (Ubiquinone); NADH-Coenzyme Q Reductase; Complex I Dehydrogenase; NADH DH I; NADH Dehydrogenase Complex 1; NADH Dehydrogenase I; NADH Q1 Oxidoreductase; NADH-Ubiquinone Oxidoreductase; NADH-Ubiquinone Reductase; Respiratory Complex I; Rotenone-Sensitive Mitochondrial NADH-Ubiquinone Oxidoreductase; Ubiquinone Reductase; Dehydrogenase, Complex I; NADH CoQ Reductase; NADH Coenzyme Q Reductase; NADH Ubiquinone Oxidoreductase; NADH Ubiquinone Reductase; Oxidoreductase, NADH Q1; Oxidoreductase, NADH-Ubiquinone; Reductase, NADH-Ubiquinone; Rotenone Sensitive Mitochondrial NADH Ubiquinone Oxidoreductase