rab1 GTP-Binding Proteins

A genetically related subfamily of RAB GTP-BINDING PROTEINS involved in vesicle transport between the ENDOPLASMIC RETICULUM and the GOLGI APPARATUS and through early Golgi compartments. This enzyme was formerly listed as EC 3.6.1.47.

Also Known As:

rab1 GTP-Binding Protein; rab1 Protein; rab1A Protein; GTP-Binding Protein, rab1; GTP-Binding Protein, rab1A; GTP-Binding Proteins, rab1; rab1 GTP Binding Protein; rab1 GTP Binding Proteins; rab1A GTP Binding Protein; rab1A GTP-Binding Protein

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Li, Chen: 1 article (11/2020)
2.	Li, Ting: 1 article (11/2020)
3.	Li, Xiangdong: 1 article (11/2020)
4.	Ling, Haibin: 1 article (11/2020)
5.	Liu, Xin: 1 article (11/2020)
6.	Su, Hongwei: 1 article (11/2020)
7.	Fan, Xin: 1 article (06/2020)
8.	Hu, Kai-Li: 1 article (06/2020)
9.	Hu, Wen-Ting: 1 article (06/2020)
10.	Sun, Xue-Hui: 1 article (06/2020)

Related Diseases

1.	Neoplasms (Cancer) 11/01/2020 - "Rab1A protein has been identified to be highly expressed in a number of malignant tumor tissues and to participate in the regulation of tumor development, but no data concerning bladder cancer have been described at present. " 11/01/2020 - "The expression levels of Rab1A protein in normal bladder cells and tissues was significantly decreased compared with that in bladder cancer cells and tissues, and it was significantly associated with tumor size, histological grade, tumor-node-metastasis (TNM) stage, lymph node metastasis and remote metastasis in 153 patients with bladder cancer. "
2.	Neoplasm Metastasis (Metastasis) 11/01/2020 - "The expression levels of Rab1A protein in normal bladder cells and tissues was significantly decreased compared with that in bladder cancer cells and tissues, and it was significantly associated with tumor size, histological grade, tumor-node-metastasis (TNM) stage, lymph node metastasis and remote metastasis in 153 patients with bladder cancer. "
3.	Lymphatic Metastasis 11/01/2020 - "The expression levels of Rab1A protein in normal bladder cells and tissues was significantly decreased compared with that in bladder cancer cells and tissues, and it was significantly associated with tumor size, histological grade, tumor-node-metastasis (TNM) stage, lymph node metastasis and remote metastasis in 153 patients with bladder cancer. "
4.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 06/01/2020 - "Western blot was used to detect the expression of RAB1A protein in human normal tongue epithelial cells (Hacat) and tongue squamous cell carcinoma Tca8113. "
5.	Urinary Bladder Neoplasms (Bladder Cancer) 11/01/2020 - "The 5-year survival rate of patients with bladder cancer with high expression levels of Rab1A protein was 48.613%, which was significantly decreased compared with the rate of patients with low expression 75.31% (P<0.05). " 11/01/2020 - "Cox regression analysis demonstrated that the expression of Rab1A protein in bladder cancer tissues was an independent risk factor for prognosis (overall risk=0.549; 95% confidence interval=0.139-0.916). " 11/01/2020 - "Western blot analysis and immunohistochemistry were used to measure the expression of Rab1A protein in normal bladder and bladder cancer cell line, and bladder cancer and normal adjacent tissues. " 11/01/2020 - "Rab1A protein has been identified to be highly expressed in a number of malignant tumor tissues and to participate in the regulation of tumor development, but no data concerning bladder cancer have been described at present. " 11/01/2020 - "The expression levels of Rab1A protein in normal bladder cells and tissues was significantly decreased compared with that in bladder cancer cells and tissues, and it was significantly associated with tumor size, histological grade, tumor-node-metastasis (TNM) stage, lymph node metastasis and remote metastasis in 153 patients with bladder cancer. "