A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.
Also Known As:
CYP2D6; Cytochrome P450 2D6; CYP 2D6; Debrisoquine 4-Monooxygenase; Imipramine 2-Hydroxylase; Sparteine Monooxygenase; 2-Hydroxylase, Imipramine; 4-Hydroxylase, Debrisoquine; 4-Monooxygenase, Debrisoquine; CYP2D6, Cytochrome P-450; Cytochrome P 450 CYP2D6; Debrisoquine 4 Hydroxylase; Debrisoquine 4 Monooxygenase; Hydroxylase, Debrisoquine; Imipramine 2 Hydroxylase; Monooxygenase, Sparteine; P-450 CYP2D6, Cytochrome; P450 2D6, Cytochrome; Debrisoquine 4-Hydroxylase; Debrisoquine Hydroxylase