Eukaryotic Initiation Factor-1

A eukaryotic initiation factor that binds to 40S ribosomal subunits. Although initially considered a "non-essential" factor for eukaryotic transcription initiation, eukaryotic initiation factor-1 is now thought to play an important role in localizing RIBOSOMES at the initiation codon of MRNA.

Also Known As:

Eukaryotic Peptide Initiation Factor-1; Eukaryotic Initiation Factor 1; Eukaryotic Peptide Initiation Factor 1; Peptide Initiation Factor EIF 1; EIF-1; Peptide Initiation Factor EIF-1

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Ribosomal Proteins: 1138
    - Peptide Initiation Factors: 1364
      - Eukaryotic Initiation Factors: 22
        Eukaryotic Initiation Factor-1: 1
        eukaryotic peptide initiation factor-1A
        human EIF1AY protein
        S cerevisiae SUI1 protein

Related Diseases

1.	Ascites 04/10/1976 - "The 133,000 X g supernatant fraction prepared from ascites cells in 20 mM KCl (low CKl supernatant) contained the initiation factors EIF-1 and EIF-2 (and the elongation factore EF-1 and EF-2) but lacked EIF-3; thus, low KCl supernatant could be used to assay for EIF-3. "

Related Drugs and Biologics

1.	Eukaryotic Initiation Factor-3
2.	Peptide Elongation Factor 2 (EF-2)
3.	Peptide Elongation Factor 1 (EF-1)
4.	Eukaryotic Initiation Factor-2 (EIF 2)
5.	Peptide Initiation Factors (Initiation Factor)