A tyrosine-specific protein kinase encoded by the v-src oncogene of ROUS SARCOMA VIRUS. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine.
Also Known As:
pp60 v-src; Avian Sarcoma Virus-Transforming Protein; Oncogene Protein src; Phosphoprotein pp60(v-src); Rous Sarcoma Virus-Transforming Protein pp60(v-src); p60(v-src); src Oncogene Product pp60; v-src Protein; Avian Sarcoma Virus Transforming Protein; Protein pp60, v-src; Protein src, Oncogene; pp60 v src; pp60, v-src Protein; src, Oncogene Protein; v src Protein; v src Protein pp60; v-src, pp60; Oncogene Protein pp60(src); pp60(v-src); src Oncogene Protein pp60; v-src Protein pp60; Kinase (phosphorylating), protein pp60src