The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
Also Known As:
Levothyroxine; Levothyroxine Sodium; Synthroid; Euthyrox; Levo-T; Levothroid; Levoxyl; Novothyrox; Sodium Levothyroxine; Thyroxin; Unithroid; 3,5,3',5'-Tetraiodothyronine; Berlthyrox; Dexnon; Eferox; Eltroxin; Eltroxine; Eutirox; L-3,5,3',5'-Tetraiodothyronine; L-Thyrox; L-Thyroxin Henning; L-Thyroxin beta; L-Thyroxine Roche; Levothyroid; Levothyroxin Deladande; Levothyroxin Delalande; Levoxine; Lévothyrox; Novothyral; O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine; O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine; Oroxine; Synthrox; Thevier; Thyrax; Tiroidine; Tiroxina Leo; L Thyrox; L Thyroxin Henning; L Thyroxin beta; L Thyroxine; L Thyroxine Roche; Levo T; Thyroid Hormone, T4; L-Thyroxine; T4 Thyroid Hormone; Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-