Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
Also Known As:
11 beta-Hydroxylase; Steroid 11 beta Hydroxylase; CYP11B1; CYP 11B1; Cytochrome P450 11B1; Steroid 11 Hydroxylase; Steroid 11-Hydroxylase; Steroid-11-Hydroxylase; 11 beta Hydroxylase; Cytochrome P 450 CYP11B1; Steroid 11 beta Monooxygenase; Cytochrome P-450 CYP11B1; Cytochrome P-450(11 beta); Steroid 11-beta-Monooxygenase; Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating)
Networked: 323
relevant articles (8 outcomes,
30 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | Gomez-Sanchez, Celso E:
11 articles
(07/2020 - 07/2002)
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2. | Hartmann, Rolf W:
11 articles
(01/2019 - 08/2010)
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3. | Sasano, Hironobu:
7 articles
(01/2022 - 07/2014)
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4. | Hu, Qingzhong:
7 articles
(01/2019 - 08/2010)
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5. | Davies, Eleanor:
7 articles
(03/2017 - 02/2005)
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6. | Nakamura, Yasuhiro:
6 articles
(01/2022 - 07/2014)
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7. | Holterhus, Paul-Martin:
6 articles
(05/2020 - 07/2006)
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8. | Riepe, Felix G:
6 articles
(05/2020 - 06/2005)
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9. | Nishimoto, Koshiro:
6 articles
(11/2019 - 05/2010)
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10. | Mukai, Kuniaki:
6 articles
(11/2017 - 05/2010)
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