Periodontal Pocket (Periodontal Pockets)

01/01/1990 - "[Efficacy of chlorhexidine on germ spectrum of periodontal pockets--an in vitro study]."
10/01/1990 - "Self-performed subgingival irrigation with 0.2% chlorhexidine is a simple method of treating isolated, deep periodontal pockets which do not respond favorably to conventional treatment techniques. "
09/01/1986 - "Previous studies have shown that a 3-day exposure of the pocket flora to the sustained release of chlorhexidine significantly reduced the relative numbers of spirochetes and motile rods in periodontal pockets to negligible amounts. "
01/01/2021 - "The results shown that the association of chlorhexidine chips to scaling and root planning reduce periodontal pocket depths (P < 0.00001; MD -0.77 [CI -1.0 to -0.55]; I2 = 23%, P = 0.24), gain on the clinical attachment level (P < 0.0001; MD -0.57 [CI -0.86 to -0.27]; I2 = 33%, P = 0.18P < 0.0001) and reduction on plaque index (P = 0.04; MD -0.23 [CI -0.45 to -0.01]; I2 = 91%, P < 0.00001). "
01/01/2020 - "Effect of chlorhexidine chip as an adjunct in non-surgical management of periodontal pockets: a meta-analysis."

03/01/2020 - "The aim of this systematic review was to explore the efficacy of different minimal invasive surgical (MIS) and non-surgical (MINST) approaches for the treatment of intra-bony defect in terms of clinical attachment level (CAL) gain and periodontal pocket depth (PPD) reduction. "
03/01/2002 - "unstimulated whole saliva flow rate (UWS) had increased, PI and periodontal pocket depth (PPD) were reduced, and general health and oral dryness and soreness had improved after using CHP. "
04/01/2023 - "Randomized controlled trials (RCTs), comparing MF plus PRF Vs PRF alone in periodontal osseous defects were identified in which periodontal pocket depth (PPD), Clinical attachment level (CAL) and Intrabony defect depth (IBD Depth) were the outcome measures. "
01/01/2023 - "It was observed that reduction in periodontal pocket depth (PPD) and increase in clinical attachment level (CAL) was seen in patients in CHX group as compared to DH treated study participants. "
01/01/2021 - "The aim of the study was to assess the influence of flap designs (Envelope flap (EF) and Szmyd flap (SF)) for impacted mandibular third molar extraction, on periodontal pocket depth (PPD), clinical attachment loss (CAL) and bone levels (BL) of second molar. "

05/01/2021 - "Determination of efficacy of curcumin and Tulsi extracts as local drugs in periodontal pocket reduction: A clinical and microbiological study."
09/01/2012 - "This in vitro and in vivo study comparatively evaluated the adjunctive efficacy of turmeric, curcumin, and traditional nonsurgical methods for treating periodontal pockets. "
11/01/2017 - "This study aimed to develop syringeable in-situ curcumin (cur) gel for the treatment of periodontal pockets as well as to evaluate the clinical efficacy of Cur in-situ gel formulation. "
02/01/2024 - "Assessment of the Efficiency of Tulsi Extract as a Locally Administered Medication Agent and Its Comparison With Curcumin in the Treatment of Periodontal Pockets."
07/01/2016 - "It can be concluded that both control and experimental gel can be used as an adjunct to SRP, but the curcumin gel was more effective than the chlorhexidine gel in the treatment of mild to moderate periodontal pockets with a significant reduction in the indice scores when compared to the baseline values."

09/01/2020 - "The aim of this study was to evaluate the clinical and antimicrobial efficacy of multiple application of PDT as an adjunct to scaling and root planning in management of moderate periodontal pockets. "
01/01/2022 - "PDT helped to reduce the clinical and pro-inflammatory load within the diseased periodontal pockets in geriatric patients."
12/02/2022 - "This article is based on a prospective clinical study involving eighteen subjects with forty-four average periodontal pockets assigned to study groups treated by two different methods, SRP and SRP followed by a single PDT application. "
12/01/2023 - "The use of ICG-mediated PDT for cavity disinfection is acceptable, but at this concentration its use in periodontal pocket disinfection is not recommended due to its cytotoxic and genotoxic properties."
07/25/2022 - "a-PDT may be useful as a noninvasive treatment in the maintenance phase, especially in patients with relatively deep periodontal pocket."

07/01/2005 - "The aim of our latest research was to test the efficacy of newly formulated preparation containing 25% metronidazole suspended in a lipogel in vitro--in anaerobic cultures isolated from the periodontal pockets, and in vivo--by the direct application into periodontal pockets. "
01/01/2022 - "In the present study, we investigated the in vitro effect of metronidazole (MTZ) at concentrations achievable in the periodontal pocket on PMN activation and PMN mediated killing of Porphyromonas gingivalis. "
04/30/2015 - "The aim of this study was to develop sustained-release metronidazole films for periodontal pockets using a computer-aided statistical approach. "
05/01/2014 - "This study was performed to obtain prolonged drug release with biodegradable in situ forming implants for the local delivery of metronidazole to periodontal pockets. "
05/01/2014 - "In situ forming implants for the delivery of metronidazole to periodontal pockets: formulation and drug release studies."

01/01/2009 - "Effect of absorbent tetracycline-loaded membrane used in the reduction of periodontal pockets: an in vivo study."
03/01/1997 - "Biodegradable microparticles for sustained delivery of tetracycline to the periodontal pocket: formulatory and drug release studies."
10/01/1992 - "The primary objective of this study was to evaluate the concentration and location of tetracycline hydrochloride in tissue adjacent to periodontal pockets treated with a tetracycline impregnated fiber. "
01/01/2001 - "The pilot clinical study indicated a mean half-time of tetracycline in GCF of 28 min with confidence intervals of 21 to 34 min, although wide variation between the drug levels of individual periodontal pockets was seen. "
01/01/2001 - "The assay was also tested in a small pilot clinical project, measuring tetracycline levels in GCF following placement of a test gel formulation in 25 periodontal pockets in 5 patients. "

11/01/1996 - "It was concluded that, for the beagle dogs with severely infected periodontal pockets in this study, treatment with subgingival doxycycline using the delivery system resulted in substantial improvement in periodontal health."
10/01/1998 - "The primary goal of this study was to characterize the release profile of doxycycline hyclate (8.5% w/w) from a biodegradable controlled-release delivery system (DH) placed in periodontal pockets. "
06/01/1988 - "The results of this study strongly suggest that surgery plus doxycycline effectively eliminate Aa from periodontal pockets. "
10/28/2019 - "Formulation and Evaluation of Novel Thiolated Intra Pocket Periodontal Composite Membrane of Doxycycline."
10/01/2004 - "Controlled-release doxycycline placed in moderate to deep periodontal pockets caused no significant additional reduction in the subgingival pathogenic microbiota compared to thorough Sc/Rp alone. "

01/01/1986 - "The purpose of this study was to determine the effectiveness of the Water Pik oral irrigator as a vehicle for delivering an aqueous solution into periodontal pockets. "
01/01/2022 - "(3) In a rat model, the GelMA-Z pregel solution was used to fill the periodontal pocket and then crosslinked by UV exposure. "
08/01/2016 - "According to protocols used in treatment, periodontal pockets were assigned to experimental and control groups as follows: CHX solution as an addition to SRP versus control SRP group; CHX gel as an addition to SRP versus control SRP; CHX chip as an addition to SRP versus control SRP group. "
04/01/1994 - "actinomycetemcomitans and microbial culture of samples collected from deep periodontal pockets and mouthrinse solution were performed. "
09/01/1991 - "The penetration of lavage solution into the periodontal pocket during ultrasonic instrumentation."

01/01/2020 - "A meta-analysis of eight studies demonstrated a mean reduction of 0.26 mm in the periodontal pockets at three months (mean difference [MD] -0.26, 95%CI: -0.36 to -0.17, n = 372 participants, moderate certainty of evidence) in favor of the antibiotics. "
06/14/2023 - "One is the use of antimicrobials to target bacteria in subgingival biofilms in the periodontal pocket, which can be targeted directly through the pocket entrance with a locally delivered antibiotic or systemically by oral, intravenous, or intramuscular methods. "
01/11/2023 - "Local sustained-release antibiotics as a complementary treatment after scaling and root planning can sustainedly combat bacterial pathogens in the periodontal pockets to help treat the disease, but the increasing concern of bacterial resistance limits its future use. "
01/01/2023 - "These approaches are directed towards establishing the levels of different periodontal pathogens in periodontal pockets to infer the antibiotic treatment. "
01/01/2023 - "Considering the drawbacks of systemic antibiotics' application, local delivery systems directly in the periodontal pocket can be helpful. "

10/01/2020 - "Laser treatment may result in a short-term decrease in periodontal pocket depth, while air powder abrasive is effective in cleaning a previously contaminated implant surface. "
05/01/1995 - "ODU Plaque-susceptible rats (ODUS/Odu) exhibit markedly heavy plaque formation in the lower incisors and develop both periodontal pockets and gingivitis after being fed a commercially available powder diet. "
01/01/1989 - "An air-powder abrasive system was tested among 20 volunteers, who had healthy gingiva or slight gingivitis, but no periodontal pockets. "
06/01/2007 - "Glycine powder air polishing (GPAP) has been shown to be significantly more effective in reducing the subgingival cultivable microflora in shallow periodontal pockets compared to curets and is safe when applied directly to root surfaces. "
04/01/2012 - "This study assesses efficacy and safety of subgingivally applied glycine powder air polishing (SubGPAP) in moderate-to-deep periodontal pockets. "

05/01/2008 - "It is suggested that bacteria may invade dentinal tubules exposed to periodontal pocket and are very hard to be eliminated by conventional mechanical and chemical periodontal therapy. "
01/01/1983 - "The results of this study indicate that significant improvement in periodontal pockets should not be expected following home care procedures alone, and that instrumentation may account for the bulk of improvement seen following a combined therapy of plaque control and instrumentation."
08/01/2018 - "Compared with participants in the control group, participants in the test group had significantly greater periodontal pocket depth, clinical attachment level, and salivary IL-1β and MMP-8 levels, and all of these parameters were significantly reduced after nonsurgical periodontal therapy. "
11/01/1985 - "Following fiber therapy, treated sites improved clinically, as evidenced by a gain in periodontal attachment and a decrease in periodontal pocket depth. "
11/01/1985 - "Following fiber therapy, treated sites improved clinically, as evidenced by a gain in periodontal attachment and a decrease in periodontal pocket depth. "

10/01/2004 - "Although these devices differ with regard to ease of use, concentration of drug delivered and length of time high drug concentrations can be maintained, randomized clinical trials have shown that their use as an adjunctive treatment to scaling and root planing results in a significantly greater reduction of periodontal pocket depth and an average increase in clinical periodontal attachment level of about 0.8 mm. Gain in clinical attachment is greater in deeper pockets than in shallower pockets. "
12/01/2008 - "The bone density within periodontal pockets treated with beneficial bacteria improved significantly after 12 weeks, while this was non-significant for the control pockets, receiving a single root planing at baseline. "
01/01/2011 - "The experimental local drug-delivery system containing 2% whole turmeric gel can be effectively used as an adjunct to scaling and root planing and is more effective than scaling and root planing alone in the treatment of periodontal pockets."
09/01/2007 - "Open root planing following flap elevation resulted in a recovery rate of 85.4% and was effective for deep and refractory periodontal pockets. "
12/01/2014 - "The aim was to evaluate the efficacy of CHX varnish and gel as an adjunct to scaling and root planing (SRP) in reducing microbial count within moderate to deep periodontal pockets. "

06/01/2007 - "The purpose of this study was to assess the subgingival debridement efficacy of GPAP in periodontal pockets with various depths. "
09/01/2005 - "Conventional surgical approaches (e.g., flap debridement) continue to offer time-tested and reliable methods to access root surfaces,reduce periodontal pockets, and attain improved periodontal form/architecture. "
10/01/1999 - "gingivalis cannot be eradicated from the great majority of deep periodontal pockets by mechanical debridement alone. "
08/01/2003 - "The findings from the present study do not support the use of EMD during routine, nonsurgical debridement of periodontal pockets as measured 3 months post SRP."
03/01/1988 - "To date, there are no ultrastructural studies that have examined untreated chronic periodontal pockets immediately following dental debridement with an oral irrigation device. "

07/01/2015 - "The aim of this retrospective multicenter study was to verify the efficacy of Nd:YAG laser in the treatment of periodontal pockets infected by Epstein-Barr Virus (EBV) and Herpes Simplex Virus 1 (HSV1). "
12/31/2021 - "The study included 909 periodontal pockets which were treated in a split-mouth design with either Gracey curettes or with Er:YAG laser (1.5 W). "
06/01/2004 - "[Antibacterial effect of Nd:YAG laser in periodontal pockets decontamination: a in vivo study]."
03/01/2003 - "In contrast to previous SEM studies, the histological examination indicated thermal changes within the hard tissue bordering the periodontal pocket following Er:YAG laser irradiation."
01/01/2022 - "Therefore, the adjunction of Nd:YAG laser (with the current setting) to the NSPT for the treatment of residual periodontal pockets did not ameliorate the clinical outcomes (ClinicalTrials.gov ID: NCT03365167)."

02/01/2017 - "It has been suggested that the use of laser radiation within the periodontal pocket may be effective in periodontal treatment. "
01/01/2022 - "The current study aimed at evaluating the application of this laser versus conventional instruments in periodontal pocket reduction flap surgery. "
05/01/2020 - "The aim of this study was to verify the sterilizing effectiveness of the laser in the treatment of the periodontal pockets in vivo, with the recording of clinicians' parameters and microbiological analysis, and in vitro with particular attention to the presence of specific bacterial stocks. "
05/01/2020 - "Laser in periodontal pockets: in vivo and in vitro study."
06/01/2004 - "The purpose of this study was to examine the removal of the epithelium in the periodontal pocket using a diode (980 nm) laser in comparison with the conventional techniques in an animal experimental model. "