O-Demethylating Oxidoreductases

Drug metabolizing enzymes which oxidize methyl ethers. Usually found in liver microsomes.

Also Known As:

Oxidoreductases, O-Demethylating; Oxidoreductases, O Demethylating; Demethylating Oxidoreductases, O; O Demethylase; O Demethylases; O Demethylating Oxidoreductases; O-Demethylase; O-Demethylases

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Chronic Hepatitis C 01/01/1993 - "Seven patients with chronic hepatitis C were treated with interferon beta at doses of 3 x 10(6) to 9 x 10(6) IU/day for 8 wk. The activities of 7-methoxycoumarin O-demethylase and 7-ethoxycoumarin O-deethylase in specimens obtained by liver biopsy were examined before and after interferon treatment. "
2.	Polyploidy 03/01/1992 - "Benzo(a)pyrene hydroxylase, ethoxyresorufin O-deethylase, and methoxycoumarin O-demethylase activities were approximately 15-40% lower in the diploid hepatocyte fraction than in the polyploid cell fraction. "
3.	Liver Cirrhosis (Hepatic Cirrhosis) 01/15/1977 - "Investigations concerning the salicylaemia in patients with liver cirrhosis and experimental findings about changes of the O-demethylase activity in the fatty degeneration of the liver show the great significance of the pharmacokinetic analyses in the clinical hepatology."

Related Drugs and Biologics

1.	Cytochrome P-450 CYP1A1 (CYP1A1)
2.	Interferon-beta
3.	7-Alkoxycoumarin O-Dealkylase
4.	Interferons
5.	Benzopyrene Hydroxylase
6.	herniarin