Insulysin (Insulin-Degrading Enzyme)
An enzyme the catalyzes the degradation of insulin, glucagon and other polypeptides. It is inhibited by bacitracin, chelating agents EDTA and 1,10-phenanthroline, and by thiol-blocking reagents such as N-ethylmaleimide, but not phosphoramidon. (Eur J Biochem 1994;223:1-5) EC 3.4.24.56.
Also Known As:
Insulin-Degrading Enzyme; Insulinase; Insulin Protease; Insulin Proteinase; Enzyme, Insulin-Degrading; Insulin Degrading Enzyme; Protease, Insulin; Proteinase, Insulin
Networked: 250
relevant articles (13 outcomes,
17 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | Leissring, Malcolm A:
16 articles
(01/2022 - 12/2003)
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2. | Tang, Wei-Jen:
10 articles
(01/2018 - 08/2007)
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3. | Morelli, Laura:
8 articles
(01/2009 - 06/2003)
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4. | Castaño, Eduardo M:
7 articles
(01/2009 - 12/2004)
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5. | Prince, Jonathan A:
6 articles
(09/2007 - 11/2003)
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6. | Cózar-Castellano, Irene:
5 articles
(01/2022 - 11/2018)
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7. | Merino, Beatriz:
5 articles
(01/2022 - 11/2018)
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8. | Perdomo, Germán:
5 articles
(01/2022 - 11/2018)
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9. | Selkoe, Dennis J:
5 articles
(01/2009 - 04/2003)
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10. | Brookes, Anthony J:
5 articles
(07/2005 - 11/2003)
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