Gels

Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.

Networked: 2620 relevant articles (160 outcomes, 264 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Gong, Jian Ping: 9 articles (04/2021 - 09/2005)
2.	Weihs, Daphne: 8 articles (03/2022 - 01/2017)
3.	Kurokawa, Takayuki: 6 articles (04/2021 - 09/2005)
4.	Stylianopoulos, Triantafyllos: 6 articles (11/2019 - 11/2010)
5.	Bissell, Mina J: 6 articles (01/2018 - 12/2006)
6.	Janmey, Paul A: 6 articles (11/2015 - 05/2005)
7.	Katas, Haliza: 5 articles (04/2022 - 01/2017)
8.	Rocco, Mattia: 5 articles (01/2021 - 03/2013)
9.	Wang, Ning: 5 articles (01/2020 - 07/2012)
10.	Gkretsi, Vasiliki: 5 articles (11/2019 - 01/2017)

Related Diseases

1.	Neoplasms (Cancer) 11/01/2018 - "Tumor spheroids on CSPG gels displayed statistically significantly greater resistance to chemotherapeutics than in the conditions where cells did not form spheroids. " 07/01/2018 - "Results of in vitro cell studies showed that all prepared gels induced CEM tumor cell migration whereas only gels based on MC embedded with CXCL12 are able to capture them." 09/01/2016 - "The prepared gels were evaluated for its gelling properties and finally studied for in vivo anti-cancer efficacy and histopathological study. " 07/01/2009 - "The 2D-DIGE study was based on 28 gels (14 cancer gels and 14 adjacent normal gels), and 732 spots were identified as matching across more than 90% of gels. " 12/01/2023 - "We have previously shown that invasive cancer cells forcefully push into and indent physiological stiffness gels to cell-scale depths, where the percentage of indenting cells and their attained depths provide clinically relevant predictions of tumor invasiveness and the potential metastatic risk. "
2.	Wounds and Injuries (Trauma) 09/01/2018 - "Histological wound and regression analysis showed that ExtEtOH gels (0.2% and 2%) were similar and effective in promoting wound healing. " 11/01/2014 - "CMHA-S films, liquids, and gels have been shown to be effective in vivo for treating various injuries and wounds in the eye in veterinary use, and are in clinical development for human use. " 02/01/2012 - "The gels promoted the accumulation of inflammatory cells such as polymorphonuclear leukocytes, which have the potential to release chemical mediators effective for wound healing, in full-thickness skin wounds in rats and accelerated the healing of the wounds. " 06/15/2020 - "Taken together, the combined properties of the co-gels, including their stability and capacity to control both cell recruitment and cell phenotype within the murine wound bed, strongly supports the potential of the co-gel scaffolds for improved treatment of chronic non-healing wounds." 12/15/2012 - "Absorption of simulated wound fluid, resultant rheological properties of gels and efficacy against plated cultures of Pseudomonas aeruginosa were measured and compared. "
3.	Pain (Aches) 07/01/1984 - "The results show that the gels were effective in reducing perceived pain for 66% of the subjects. " 01/01/2020 - "This review found that these drugs, delivered topically as adhesive gels or similar preparations, may be more effective than placebo for reducing the pain of symptomatic OLP; however, with the small number of studies and participants, our confidence in the reliability of this finding is low. " 01/01/2020 - "Stability and standardization of a defined amount or concentrations of herbal gels would give promising effects on OA treatment and pain relief." 01/01/2020 - "Herbal gels have demonstrated robustly significant healing effects on knee pain, stiffness and mobility. " 04/01/2017 - "Paired samples t test was used to compare the mean pain score between the two gels. "
4.	Infections 08/01/2004 - "The results of this clinical study indicate that better therapeutic efficacy can be achieved using gels for treating oral infections than conventional treatments using mouthwash." 01/01/2012 - "The gels were found to be effective spreading gels, exhibited limited toxicity in vitro, caused minimal damage to the architecture of the cervicovaginal and rectal mucosae in vivo, and induced no increased susceptibility to HSV-2 infection in a mouse model. " 10/01/1996 - "When Trypanosoma brucei brucei-infected mice are treated topically with these gels the circulating trypanosomes are rapidly cleared from the circulation but the infections relapse soon after the last application. " 12/01/2015 - "In this study, PVA gels with varying constituents that were manufactured via a refreeze/thawing route, were found to have excellent potential for antimicrobial delivery for bone infections. " 06/01/2001 - "In the present study we have compared three commercial software packages, GelCompar, Molecular Analyst Fingerprinting, and BioImage, to determine if the results generated by the programs were comparable and correlated adequately with visual interpretation of electrophoretic gels, in the analysis of several well characterized incidents of infections. "
5.	Acne Vulgaris 05/01/2023 - "IDP-126 gel-a novel fixed-dose, triple-combination topical formulation for acne-demonstrated superior efficacy to vehicle and three dyad component gels and was well tolerated in children and adolescents with moderate-to-severe acne." 06/01/2017 - "The results suggest that both 2.5% and 5% BPO gels are effective and safe for long-term treatment of patients with acne vulgaris." 05/01/2023 - "In a randomized, double-blind phase 2 study (NCT03170388), participants ≥9 years of age with moderate-to-severe acne were eligible for randomization (1:1:1:1:1) to once-daily IDP-126, one of three dyad combination gels, or vehicle gel for 12 weeks. " 02/01/2013 - "Our study shows that CLNP-BPO5 or CLNP-BPO2.5 fixed-dose gels in combination with TZ cream 0.1% are generally well-tolerated and effective treatments of moderate to severe facial acne when applied once daily for up to 12 weeks." 10/01/2009 - "Study of the efficacy, tolerability, and safety of 2 fixed-dose combination gels in the management of acne vulgaris."

Related Drugs and Biologics

1.	Hydrogels
2.	Proteins (Proteins, Gene)
3.	Peptides (Polypeptides)
4.	Adapalene (Differin)
5.	Collagen
6.	Chlorhexidine
7.	tazarotene (Tazorac)
8.	Ointments (Pastes)
9.	Sepharose (Agarose)
10.	Liposomes (Liposome)

Related Therapies and Procedures

1.	Therapeutics
2.	Injections
3.	Root Planing
4.	Semiconductor Lasers
5.	Enema (Enemas)