Dimethylhydrazines

03/01/1991 - "The aim of the present study was to characterize rat mucosal colonic cells harvested from the crypt continuum during differentiation and dimethylhydrazine-induced neoplasia. "
09/01/2007 - "No tumors developed in dimethylhydrazine-free groups. "
09/01/2006 - "In the dimethylhydrazine group, fecal absence altered the number of tumors developing in males as compared to female rats (p = 0.025). "
09/01/2006 - "no tumors developed in the dimethylhydrazine-free groups. "
06/01/1992 - "Tumor induction in monkeys after administration of dimethylhydrazine."

10/01/2022 - "Colon cancer was induced by dimethylhydrazine. "
04/01/2020 - "The drug release profiles of NPs were monitored under different pH, and their cytotoxic effects were assessed in vitro against Caco-2 cells and in vivo against dimethylhydrazine-induced colon cancer in mice. "
01/01/2013 - "Thirty Sprague-Dawley rats (4 months old) were experimentally treated with procarcinogen dimethylhydrazine to induce colon cancer development. "
03/01/2008 - "Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats."
05/01/1998 - "Effect of oyster mushroom (Pleurotus ostreatus) on pathological changes in dimethylhydrazine-induced rat colon cancer."

01/01/2002 - "In dimethylhydrazine-treated and control rats, crypt cell mitosis was suppressed at 48 h and 42 days after injection, and there was a statistically significant reduction in the number of aberrant crypts and larger aberrant crypt foci (> 4 crypts/focus) in the distal colon of treated animals. "
07/01/2010 - "Astragalosides might reduce the number of colorectal aberrant crypt foci induced by dimethylhydrazine possibly by reducing the content of hepatic CYP450 and increasing GST activity in rats."
05/01/2016 - "In addition, oral administration of 500 mg/kg bw extract for 10 weeks significantly decreased the number of hepatic GST placental form positive foci, but did not modulate the number of colonic aberrant crypt foci in DEN- and dimethylhydrazine-initiated rats. "
02/01/1996 - "Epithelial proliferation, aberrant crypt foci (ACF), and tumors were measured 6 and 20 weeks after a 10-week course of dimethylhydrazine. "
07/01/2010 - "[Effects of astragalosides on induction of colorectal aberrant crypt foci by dimethylhydrazine and metabolizing enzymes in liver microsomes in rats]."

05/01/1998 - "In order to study the influence of fiber supplements on dimethylhydrazine induction of colon tumorigenesis six-week-old CD1 (ICR): Crj mice were injected i.m. "
02/09/2022 - "An Integrative Approach to Characterize the Early Phases of Dimethylhydrazine-Induced Colorectal Carcinogenesis in the Rat."
10/15/2015 - "Effect of Rumex Abyssinicus on preneoplastic lesions in dimethylhydrazine induced colon carcinogenesis in rats."
05/01/2015 - "Morphofunctional parameters of blood cells of the rats with dimethylhydrazine induced colon carcinogenesis have been investigated. "
08/01/2013 - "Açai (Euterpe oleracea Mart.) feeding attenuates dimethylhydrazine-induced rat colon carcinogenesis."

05/01/2014 - "This study shows value of discriminate analysis of urine fluorescent fingerprint between healthy control group of rats and those with dimethylhydrazine induced early lesions of colorectal cancer. "
01/01/2022 - "The Antitumor Activity of Ginger against Colorectal Cancer Induced by Dimethylhydrazine in Rats."
10/01/2020 - "Rats in model group were subcutaneously injected with dimethylhydrazine (25 mg/kg) to establish the model of colorectal cancer. "
01/01/2020 - "The Antitumor Activity of a Novel Fluorobenzamidine against Dimethylhydrazine- Induced Colorectal Cancer in Rats."
12/01/1999 - "These data suggest that in the dimethylhydrazine rat model of colorectal cancer, the Apc gene is mutated in early stages, albeit to a lesser degree than observed in human colorectal cancer, whereas the mutational hot spot of the p53 gene for human colorectal cancer is not commonly mutated. "