Cortisone Reductase

An enzyme that catalyzes the interconversion of a ketone and hydroxy group at C-20 of cortisone and other 17,20,21-trihydroxy steroids. EC 1.1.1.53.

Also Known As:

3 alpha,20 beta Hydroxysteroid Dehydrogenase; 20 beta Hydroxysteroid Dehydrogenase; Dehydrogenase, 20-beta-Hydroxysteroid; Reductase, Cortisone; 20-beta-Hydroxysteroid Dehydrogenase; 3 alpha(or 20 beta)-Hydroxysteroid:NAD+ oxidoreductase

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Alcohol Oxidoreductases: 56
      - NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
        20-Hydroxysteroid Dehydrogenases
        Cortisone Reductase: 1

Experts

1.	Debaveye, Yves: 1 article (06/2022)
2.	Derese, Inge: 1 article (06/2022)
3.	Langouche, Lies: 1 article (06/2022)
4.	Pauwels, Lies: 1 article (06/2022)
5.	Téblick, Arno: 1 article (06/2022)
6.	Van Aerde, Nathalie: 1 article (06/2022)
7.	Van Dyck, Lisa: 1 article (06/2022)
8.	Van den Berghe, Greet: 1 article (06/2022)
9.	Van der Perre, Sarah: 1 article (06/2022)
10.	Vanhorebeek, Ilse: 1 article (06/2022)

Related Diseases

Critical Illness (Critically Ill)

06/01/2022 - "In freshly-isolated neutrophils and monocytes and in skeletal muscle and subcutaneous adipose tissue of 137 critically ill patients and 20 healthy controls and in skeletal muscle and adipose tissue as well as in vital tissues (heart, lung, diaphragm, liver, kidney) of 88 septic and 26 healthy mice, we quantified gene expression of cortisone-reductase 11β-HSD1, glucocorticoid-receptor-isoforms GRα and GRβ, GRα-sensitivity-regulating-co-chaperone FKBP51, and GR-action-marker GILZ. "

Related Drugs and Biologics

1.	Protein Isoforms (Isoforms)
2.	Glucocorticoid Receptors (Glucocorticoid Receptor)