Matrix Gla Protein

11/01/2019 - "In matrix Gla protein-deficient mice, a model of human vascular calcification, mice lacking HDAC9 had a 40% reduction in aortic calcification and improved survival. "
01/01/2023 - "Matrix Gla protein (MGP) is a robust innate suppressor of the detrimental process of vascular calcification in the human body. "
01/01/2023 - "The results were reported in the change of coronary artery calcification (CAC) scores, other artery and valve calcification, vascular stiffness, and dephospho-uncarboxylated matrix Gla protein (dp-ucMGP). "
12/15/2021 - "Matrix Gla protein (MGP), a local inhibitor of tissue mineralization, is associated with vascular calcification. "
02/23/2020 - "Matrix Gla protein (MGP) is a major inhibitor of soft tissue calcification and contributes to preventing both intimal and medial vascular calcification. "

01/01/2022 - "Association of desphospho-uncarboxylated matrix gla protein with incident cardiovascular disease and all-cause mortality: Results from the prospective Bruneck Study."
01/01/2018 - "This study aims to investigate whether plasma matrix Gla protein (MGP) species, desphospho-uncarboxylated (dp-uc) MGP, and total uncarboxylated (t-uc) MGP are associated with plaque levels of uncarboxylated (uc) MGP, markers of plaque stability, and cardiovascular disease (CVD) risk. "
12/01/2022 - "Circulating uncarboxylated matrix Gla protein (ucMGP) is possibly related to coronary arterial calcification (CAC) in cardiovascular disease (CVD) patients. "
01/01/2022 - "MGP (matrix Gla protein) is implicated in vascular calcification in animal models, and circulating levels of the uncarboxylated, inactive form of MGP (ucMGP) are associated with cardiovascular disease-related and all-cause mortality in human studies. "
11/01/2013 - "To investigate the relationship of circulating matrix Gla protein (MGP) species with incident cardiovascular disease (CVD) or coronary heart disease (CHD) in type 2 diabetic patients. "

10/01/2022 - "Increased Dephospho-uncarboxylated Matrix Gla-Protein Is Associated With Lower Axial Skeletal Muscle Mass in Patients With Hypertension."
09/01/2008 - "Renal handling of matrix Gla-protein in humans with moderate to severe hypertension."
09/01/2008 - "Since a decrease in renal clearance is a prevalent clinical problem in patients with hypertension, we aimed to study the renal clearance of matrix Gla-protein from the circulation in these patients having a wide range of creatinine clearances. "
01/01/2018 - "Aldosterone, inactive matrix gla-protein, and large artery stiffness in hypertension."

09/01/2008 - "In these patients, renal arterial and renal venous blood was sampled prior to the administration of contrast material in order to determine the total renal and single kidney clearance of matrix Gla-protein. "

01/01/2023 - "Mechanistically, our study showed that reduced APPL1 impaired the osteogenic differentiation of mesenchymal stem cells by facilitating Matrix Gla protein expression to disrupt the BMP2 pathway in osteoporosis. "
01/01/2019 - "Objective: Studies suggest that matrix Gla protein (MGP) is associated with osteoporosis. "
02/16/2022 - "To investigate the relationships among serum glucagon-like peptide-1 (GLP-1) levels, matrix Gla protein (MGP) levels, and diabetes with osteoporosis. "
02/16/2022 - "Significance of serum glucagon-like peptide-1 and matrix Gla protein levels in patients with diabetes and osteoporosis."
12/01/2015 - "Vitamin K-dependent matrix Gla protein (MGP) has been known as a potent inhibitor of arterial calcification and osteoporosis. "