Centrosomal Associated Proteins

07/01/2022 - "Centrosomes in these malignancies display both numerical and structural aberrations, including alterations in the number and size of centrioles, inappropriate post-translational modification of centrosomal proteins, and extra centrosome clustering. "
12/01/2021 - "Centrosomal-associated Proteins: Potential therapeutic targets for solid tumors?"
01/01/2019 - "Centrosomal Proteins in Urothelial Tumors: New Pathways in Disease Pathogenesis."
01/01/2018 - "New research on cancer cell centrosomes has generated new insights into centrosome dysfunctions in cancer cells in which centrosome phosphorylation, balance of centrosomal proteins, centrosome regulation and duplication are impaired. "
05/01/2002 - "The model might also apply to several other centrosomal proteins that have been linked to cancer."

05/30/2014 - "Human genetic studies have established a link between a class of centrosome proteins and microcephaly. "
12/01/2021 - "Many primary microcephaly mutations occur in genes that encode centrosome proteins, highlighting an important role for centrosomes in cortical development. "
01/01/2021 - "While the centrosome is ubiquitously present, mutations of centrosome proteins are strongly associated with human microcephaly characterized by a small cerebral cortex, underscoring the importance of an intact centrosome in supporting cortical neurogenesis. "
01/01/2019 - "Primary microcephaly is caused by mutations in genes encoding centrosomal proteins including WDR62 and KIF2A. "
09/17/2013 - "Several centriole and centrosome proteins have been linked to microcephaly (MCPH), a neuro-developmental disease associated with small brain size. "

11/01/2012 - "Thus, this study aimed to examine the expression of Aurora family kinase and various centrosomal proteins, including centrin, γ-tubulin, and hNinein isoforms, in human brain tumors, including 29 meningiomas, 34 astrocytomas, 6 pituitary adenomas, and 6 metastatic tumors. "

11/01/2012 - "Thus, this study aimed to examine the expression of Aurora family kinase and various centrosomal proteins, including centrin, γ-tubulin, and hNinein isoforms, in human brain tumors, including 29 meningiomas, 34 astrocytomas, 6 pituitary adenomas, and 6 metastatic tumors. "

11/01/2012 - "Differential expression of centrosomal proteins of brain tumors and cell lines was observed. "
11/01/2012 - "Thus, this study aimed to examine the expression of Aurora family kinase and various centrosomal proteins, including centrin, γ-tubulin, and hNinein isoforms, in human brain tumors, including 29 meningiomas, 34 astrocytomas, 6 pituitary adenomas, and 6 metastatic tumors. "