Compulsive Sexual Behavior Disorder

Persistent pattern of failure to control intense, repetitive sexual impulses or urges resulting in repetitive sexual behavior. Symptoms may include repetitive sexual activities becoming a central focus of the person’s life to the point of neglecting health and personal care or other interests, activities and responsibilities; numerous unsuccessful efforts to significantly reduce repetitive sexual behavior; and continued repetitive sexual behavior despite adverse consequences or deriving little or no satisfaction from it. (https://icd.who.int/browse11/l-m/en#/http://id.who.int/icd/entity/1630268048)

Also Known As:

Addiction, Sex; Addiction, Sexual; Addictions, Sex; Addictions, Sexual; Behavior, Compulsive Sexual; Behaviors, Compulsive Sexual; Compulsive Sexual Behaviors; Compulsiveness, Sexual; Compulsivenesses, Sexual; Disorder, Hypersexuality; Disorders, Hypersexuality; Hypersexuality Disorders; Obsession, Sexual; Obsessions, Sexual; Sex Addictions; Sex, Addictive; Sexaholisms; Sexual Addictions; Sexual Behavior, Compulsive; Sexual Behaviors, Compulsive; Sexual Compulsivenesses; Sexual Obsessions; Addictive Sex; Compulsive Sexual Behavior; Hypersexuality Disorder; Sex Addiction; Sexaholism; Sexual Addiction; Sexual Compulsiveness; Sexual Obsession

Networked: 77 relevant articles (10 outcomes, 6 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Gambling (Pathological Gambling)
2.	Borderline Personality Disorder (Personality Disorders, Borderline)
3.	Paraphilic Disorders (Paraphilia)
4.	Disruptive, Impulse Control, and Conduct Disorders (Kleptomania)
5.	Mental Disorders (Mental Disorder)

Experts

1.	Diehl, Alessandra: 5 articles (05/2019 - 04/2016)
2.	Grant, Jon E: 3 articles (01/2020 - 02/2010)
3.	Clemente, Jales: 3 articles (05/2019 - 09/2017)
4.	Pillon, Sandra Cristina: 3 articles (10/2017 - 04/2016)
5.	Kraus, Shane W: 2 articles (01/2022 - 12/2020)
6.	Lewczuk, Karol: 2 articles (01/2022 - 01/2020)
7.	Dhejne, Cecilia: 2 articles (07/2021 - 01/2020)
8.	Jokinen, Jussi: 2 articles (07/2021 - 01/2020)
9.	Savard, Josephine: 2 articles (07/2021 - 01/2020)
10.	Reid, Rory C: 2 articles (12/2020 - 11/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Compulsive Sexual Behavior Disorder:

1.	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 02/13/2023 - "Treatment with selective serotonin reuptake inhibitors was commenced, and psychologically he was managed with techniques specific to compulsive sexual behavior. " 01/01/2020 - "Selective serotonin reuptake inhibitors seem the first-line pharmacological treatment for sexual addiction. " 11/01/2000 - "The author presents two cases of nonparaphilic sexual addiction (NPSA) with comorbid depression and other psychiatric disorders in which symptoms were relieved during treatment with selective serotonin reuptake inhibitors. " 01/01/2000 - "The link between serotonergic dysfunction and the pathophysiology of impulsivity is discussed, and studies that examine the efficacy of various selective serotonin reuptake inhibitors and other alternatives in the treatment of impulsive disorders such as pathological gambling, sexual addictions and borderline personality disorder are presented." 04/01/2000 - "Recent reports suggest that individuals with nonparaphilic compulsive sexual behavior can be treated pharmacologically with selective serotonin reuptake inhibitors (SSRIs) to control sexual obsessions and compulsions. "
2.	Naltrexone (ReVia)FDA LinkGeneric 06/01/2022 - "The literature review has shown that patients' symptoms were improved in different doses without side effects, and based on this and our experience, it can be said that naltrexone is effective in the reduction and remission of the symptoms of CSB or sexual addiction." 01/01/2020 - "Naltrexone in Compulsive Sexual Behavior Disorder: A Feasibility Study of Twenty Men. " 01/01/2020 - "Naltrexone in Compulsive Sexual Behavior Disorder: A Feasibility Study of Twenty Men." 02/15/2018 - "Compulsive Sexual Behaviors Treated With Naltrexone Monotherapy." 02/01/2010 - "Augmentation with naltrexone to treat compulsive sexual behavior: a case series."
3.	Fluoxetine (Prozac)FDA LinkGeneric 09/01/2022 - "Use of Fluoxetine in Treating Compulsive Sexual Behavior: A Case Report." 08/01/1999 - "Fluoxetine and compulsive sexual behavior." 11/01/1994 - "Sexual obsessions associated with fluoxetine." 10/01/1992 - "Fluoxetine treatment of nonparaphilic sexual addictions and paraphilias in men." 08/15/2007 - "Case report: lamotrigine/fluoxetine combination in the treatment of compulsive sexual behavior."
4.	Cyproterone AcetateIBA 10/01/1998 - "Anti-androgenic agent cyproterone acetate cured a woman of severe sexual obsessions." 04/01/2013 - "Episodic sexual addiction in a depressed woman treated with cyproterone acetate." 01/01/2009 - "Relevant publications were identified through a search of the English-language literature indexed on MEDLINE/PubMed (1966-September 2008) using the search terms paraphilia, sex offender, hypersexuality, sexual behaviors, fetish, transvestic fetishism, sexual addiction, sexual compulsivism, selective serotonin reuptake inhibitors, tricyclic antidepressants, antiandrogens, cyproterone acetate, medroxyprogesterone acetate, LHRH agonists, and estrogens. "
5.	Serotonin (5 Hydroxytryptamine)IBA 09/01/2008 - "Serotonin reuptake blockers seem to be effective in the treatment of sexual obsessions or compulsions and less on paraphilic disturbances. " 10/01/1992 - "Paraphilias (PAs) and non-paraphilic sexual addictions (NPSAs) may be behaviors that share a common perturbation of central serotonin neuroregulation as a component of their pathophysiology. " 08/01/1992 - "Paraphilias and related disorders may be less responsive than sexual obsessions or compulsions to serotonin reuptake blockers. "
6.	LithiumIBA 01/01/2012 - "Use of lithium for sexual obsessions in Asperger's disorder." 02/01/1991 - "Nine of 10 consecutively evaluated men with DSM-III-R nonparaphilic sexual addictions or paraphilias noted improvement in sexual behaviors and depressive symptomatology while treated with fluoxetine, imipramine, or lithium. "
7.	Paroxetine (Paxil)FDA LinkGeneric 09/01/2016 - "Discussion Paroxetine treatment, although seemingly initially effective in reducing pornography use and anxiety, appeared related to new compulsive sexual behaviors after 3 months. "
8.	Imipramine (Janimine)FDA LinkGeneric 02/01/1991 - "Nine of 10 consecutively evaluated men with DSM-III-R nonparaphilic sexual addictions or paraphilias noted improvement in sexual behaviors and depressive symptomatology while treated with fluoxetine, imipramine, or lithium. "
9.	Clomipramine (Anafranil)FDA LinkGeneric 01/01/1995 - "Two cases of sexual addiction for more than five years treated with psychological treatment and clomipramine showed marked improvement after six to nine months. " 01/01/1995 - "Response of clomipramine in sexual addiction."
10.	nefazodone (Serzone)FDA LinkGeneric 04/01/2000 - "Results from this preliminary retrospective study suggest that nefazodone decreases the frequency of sexual obsessions and compulsions but does not produce the undesired sexual side effects caused by SSRI treatment." 04/01/2000 - "Fourteen subjects who met DSM-IV criteria for sexual disorder NOS as well as criteria used by our research group for nonparaphilic compulsive sexual behavior and who had been treated with nefazodone were selected from patient charts at our clinic. " 04/01/2000 - "We examined retrospective data from our clinic to investigate whether nefazodone has utility in the treatment of nonparaphilic compulsive sexual behavior. " 04/01/2000 - "Nefazodone and the treatment of nonparaphilic compulsive sexual behavior: a retrospective study." 04/01/2000 - "Of the subjects who remained on long-term nefazodone therapy, 6 (55%) reported good control of sexual obsessions and compulsions, and 5 (45%) reported a remission of sexual obsessions and compulsions. "

Therapies and Procedures

1.	Therapeutics 01/01/2018 - "The possibilities of therapy of love and sexual addiction are analyzed. " 01/01/2018 - "Current treatment protocols for hypersexuality and sexual addiction were reviewed, as were current concepts in existential therapy. " 01/01/2018 - "To explore the relation between the existential phenomenon of death anxiety and hypersexuality (ie, sexual addiction) and present an evaluation and treatment paradigm that is rooted in existential psychotherapy, a form of psychotherapy that is a deeply life-affirming and dynamic approach to therapy that focuses on concerns rooted in the individual's existence. " 08/18/2017 - "Testing the Effectiveness of Cognitive Analytic Therapy for Hypersexuality Disorder: An Intensive Time-Series Evaluation." 12/01/2008 - "The evolution and accessibility of the Internet only raises greater concerns about compulsive sexual behavior, as more adolescents are brought into therapy because of Internet use to seek sexual interaction or stimulation. "
2.	Transcranial Direct Current Stimulation 01/01/2015 - "A bibliographic search has been conducted on the Medline and ScienceDirect databases until December 2014, based on the following selection criteria: clinical studies on tDCS and BA (namely eating disorders, compulsive buying, Internet addiction, pathological gambling, sexual addiction, sports addiction, video games addiction). "
3.	Drug Therapy (Chemotherapy) 01/01/2020 - "Pharmacotherapy of Sexual Addiction." 06/01/2022 - "This case report also includes a literature review of pharmacotherapy, especially naltrexone, for the treatment of sexual addiction/compulsive sexual behavior. "
4.	Secondary Prevention 02/01/2018 - "Section II focuses on specific psychosocial interventions including brief interventions, relapse prevention, cognitive behavioural interventions, psychoanalytical interventions, cognitive rehabilitation, interventions in dual disorders, marital and family therapy, psychosocial interventions for sexual dysfunction and sexual addictions. "
5.	Transcranial Magnetic Stimulation 01/01/2020 - "Positive Response of Compulsive Sexual Behavior to Transcranial Magnetic Stimulation."