Anthrones

11/27/1995 - "The present study investigated a possible role for Ca2+ in skin tumor promotion by anthrones. "
11/27/1995 - "Collectively, the data suggest a possible role for Ca2+ in the process of skin tumor promotion by anthrones."
10/01/1990 - "Moreover, we have recently shown that the relative tumor promoting activity of a series of structurally related anthrones correlated with their ability to undergo base-catalyzed oxidation. "
01/01/1989 - "In addition, the data suggest that epidermal toxicity may play a role in tumor promotion by anthrones."
12/01/1993 - "The current results provide further support for a role of reactive oxygen species in the tumor promoting activity of anthrones. "

12/01/1996 - "1. Antipsoriatic anthrones are among the most commonly used topical agents for the treatment of psoriasis. "
01/01/1995 - "Antipsoriatic anthrones are probably the most commonly used topical agents in the treatment of psoriasis. "
01/01/1995 - "Treatment of psoriasis with anthrones-chemical principles, biochemical aspects, and approaches to the design of novel derivatives."

12/01/1996 - "4. This article summarizes the evidence pointing toward the significance of oxygen activation and radical formation in the antipsoriatic action and induction of skin inflammation of anthrones. "
01/01/1995 - "These species are involved in a variety of oxidative effects affecting cellular targets that have been implicated both in the mode of action and the skin-irritating properties of antipsoriatic anthrones: interaction with DNA, inhibition of various enzyme systems associated with cell proliferation and inflammation, such as glucose-6-phosphate dehydrogenase and inflammation, such as glucose-6-phosphate dehydrogenase and 5-lipoxygenase, and destruction of membrane lipids. "

10/01/2019 - "1,8-Substituted anthraquinones, anthrones and bianthrones as potential non-azole leads against fungal infections."

07/30/2017 - "Some of these plants need to be stored at least one year before they can be used in order to oxidize anthrones into oxanthrones, so to avoid severe diarrhea and dehydration. "