Aortic Intramural Hematoma

An atypical form of AORTIC DISSECTION in which subintimal dissection of the aortic TUNICA MEDIA without initial laceration of the aortic TUNICA INTIMA. It may begin from a rupture of the VASA VASORUM feeding aortic media.

Also Known As:

Networked: 37 relevant articles (0 outcomes, 6 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Aortic Dissection
2.	Thoracic Aortic Aneurysm
3.	Penetrating Atherosclerotic Ulcer
4.	Ulcer
5.	Cardiovascular Diseases (Cardiovascular Disease)

Experts

1.	Li, Jun: 3 articles (01/2021 - 01/2020)
2.	Dexter, David J: 2 articles (01/2022 - 01/2020)
3.	Lin, Maggie J: 2 articles (01/2022 - 01/2020)
4.	Mesar, Tomaz: 2 articles (01/2022 - 01/2020)
5.	Panneton, Jean M: 2 articles (01/2022 - 01/2020)
6.	Rathore, Animesh: 2 articles (01/2022 - 01/2020)
7.	Wang, Daoquan: 2 articles (01/2021 - 01/2020)
8.	Xiong, Sizheng: 2 articles (01/2021 - 01/2020)
9.	Xu, Xia: 2 articles (01/2021 - 01/2021)
10.	Ehara, Natsuhiko: 2 articles (01/2014 - 09/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Aortic Intramural Hematoma:

1.	Proteins (Proteins, Gene)FDA Link 01/01/2014 - "The present study aimed to determine the prognostic significance of serial C-reactive protein measurements for the prediction of adverse events in patients with acute aortic intramural hematoma. "
2.	L 644711 (B-3(+))IBA 10/30/2023 - "This study comprised 173 patients (mean age=58±13, range=28-83, 148 men) with thoracic aortic pathologies, including 44 thoracic aortic aneurysms, 113 aortic dissections (9 type A, 4 residual type A, 75 type B, 32 non-A non-B), 3 aortic intramural hematomas, and 13 penetrating aortic ulcers. "
3.	Oraconal (Serial C)IBA 01/01/2014 - "The present study aimed to determine the prognostic significance of serial C-reactive protein measurements for the prediction of adverse events in patients with acute aortic intramural hematoma. "
4.	Contrast MediaIBA 05/01/2009 - "Characteristic findings of an aortic intramural hematoma include a crescentic hyperattenuating fluid collection at unenhanced computed tomography (CT) and a smooth, nonenhancing, thickened aortic wall at contrast material-enhanced CT. " 04/01/2011 - "To investigate the prevalence, fate, and effect of focal contrast enhancement lesion within the hematoma on contrast material-enhanced computed tomographic (CT) images in patients with distal aortic intramural hematoma (IMH). "
5.	C-Reactive ProteinIBA 11/12/2019 - "Correlation between C-reactive Protein and Morphology of Aortic Intramural Hematoma on CT Angiography." 01/01/2014 - "Prognostic value of sustained elevated C-reactive protein levels in patients with acute aortic intramural hematoma." 01/01/2014 - "C-reactive protein was a simple and useful marker providing incremental prognostic information compared with the development of an ulcer-like projection in patients with aortic intramural hematoma."
6.	rho-Associated KinasesIBA 12/02/2020 - "RCAN1 reduction protects against atherosclerosis by reducing the uptake of oxidized low-density lipoproteins, whereas RCAN1 has a protective effect on myocardial ischemia/reperfusion injury, myocardial hypertrophy and intramural hematoma/aortic rupture mainly mediated by maintaining mitochondrial function and inhibiting calcineurin and Rho kinase activity, respectively. "
7.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/01/2019 - "Predictive value of 18F-FDG PET/CT in patients with acute type B aortic intramural hematoma."
8.	CalcineurinIBA 12/02/2020 - "RCAN1 reduction protects against atherosclerosis by reducing the uptake of oxidized low-density lipoproteins, whereas RCAN1 has a protective effect on myocardial ischemia/reperfusion injury, myocardial hypertrophy and intramural hematoma/aortic rupture mainly mediated by maintaining mitochondrial function and inhibiting calcineurin and Rho kinase activity, respectively. "
9.	LDL Lipoproteins (beta Lipoproteins)IBA 12/02/2020 - "RCAN1 reduction protects against atherosclerosis by reducing the uptake of oxidized low-density lipoproteins, whereas RCAN1 has a protective effect on myocardial ischemia/reperfusion injury, myocardial hypertrophy and intramural hematoma/aortic rupture mainly mediated by maintaining mitochondrial function and inhibiting calcineurin and Rho kinase activity, respectively. "

Therapies and Procedures

1.	Endovascular Aneurysm Repair 02/21/2019 - "However no prior studies have reported an aortic intramural hematoma (IMH) as a presentation of GCA or outcome of thoracic endovascular aortic repair (TEVAR) in TAA or IMH secondary to GCA. " 01/01/2022 - "Thoracic endovascular aortic repair (TEVAR) is increasingly utilized in the management of acute type B aortic intramural hematoma (TBIMH). " 01/01/2022 - "Impact of thoracic endovascular aortic repair timing on aortic remodeling in acute type B aortic intramural hematoma." 01/01/2021 - "Thoracic Endovascular Aortic Repair for Aberrant Subclavian Artery and Stanford Type B Aortic Intramural Hematoma." 01/01/2021 - "Objectives: To evaluate the effects of thoracic endovascular aortic repair (TEVAR) in descending aorta for retrograde type A aortic intramural hematoma (re-TAIMH). "
2.	Therapeutics 07/29/2023 - "This study aimed to investigate the short-term predictors of aortic-related adverse events in patients with acute type B aortic intramural hematoma (IMH) initially treated with optimized medical therapy.A total of 157 patients with acute type B IMH were included in this study. " 07/29/2023 - "Analysis of Short-Term Clinical Outcomes and Influencing Factors in Patients with Acute Type B Aortic Intramural Hematoma Treated with Optimal Medical Therapy." 01/01/2020 - "Medical therapy in type B aortic intramural hematoma is associated with a high failure rate." 09/01/2015 - "The choice of therapy in patients with aortic intramural hematoma is difficult and should be based on comprehensive evaluation of the patient's status as well as on the experience of the radiologist and surgeon. " 09/15/2009 - "Clinical outcomes of medical therapy and timely operation in initially diagnosed type a aortic intramural hematoma: a 20-year experience."
3.	Stents 10/01/2018 - "This study aimed to describe our experience with the management and the results of stent-graft (SG) repair of acute type B aortic intramural hematoma (B-IMH). " 10/01/2018 - "Best Medical Treatment and Selective Stent-GraftRepair for Acute Type B Aortic Intramural Hematoma." 10/01/2017 - "Endovascular Stent Graft Repair of Localized Acute Aortic Intramural Hematoma: A Case Report and Literature Review." 03/01/2014 - "To determine the clinical value of dual-source CT angiography (DSCTA) in the diagnosis of postoperative aortic intramural hematoma (AIMH) in patients with endovascular stent-graft exclusion (EVE) surgery. " 03/01/2014 - "[Clinical value of dual-source CT angiography in the diagnosis of postoperative aortic intramural hematoma in patients with endovascular stent-graft exclusion surgery]."
4.	Conservative Treatment 01/01/2021 - "There were 120 patients with Stanford type B aortic intramural hematoma (71.4%), 60 patients received endovascular treatment (50%), and 60 patients (50%) received conservative treatment, with an average follow-up of (27.8 ± 14.6) months. " 01/01/2021 - "For patient with Stanford A aortic intramural hematoma, endovascular treatment was performed in 15 patients (31.2%), and 33 cases (68.8%) for conservative treatment. " 07/01/2020 - "Successful Conservative Treatment of a Type A Aortic Intramural Hematoma." 12/15/2010 - "A computed tomographic scan revealed aortic intramural hematoma; thus, conservative therapy was performed. " 01/01/2014 - "Aggressive management with interventional radiology for hepatic pseudoaneurysm and conservative management of the aortic intramural hematoma resulted in favorable outcome for our patient."
5.	Laryngoscopes 01/01/2021 - "The patient was in good health and had no history of cardiovascular disease, throat disease, diabetes, asthma, tumor, etc. The left vocal cord paralysis was seen by electronic laryngoscope, and aortic intramural hematoma was found by chest CT examination. "