Molar Hypomineralization

A type of developmental disturbance of AMELOGENESIS involving MOLARS of any type (obligatory) plus other teeth sometimes. It is characterized by demarcated enamel opacities with unknown systemic causation (idiopathic).

Also Known As:

Molar Incisor Hypomineralization; Hypomineralization, Incisor; Hypomineralization, Incisor Molar; Hypomineralization, Molar; Hypomineralization, Molar Incisor; Incisor Hypomineralizations; Incisor Molar Hypomineralizations; Molar Hypomineralization, Incisor; Molar Hypomineralizations; Molar Incisor Hypomineralizations; Incisor Hypomineralization; Incisor Molar Hypomineralization

Networked: 104 relevant articles (4 outcomes, 22 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Molar Hypomineralization
2.	Hypersensitivity (Allergy)
3.	Dental Caries (Decay, Dental)
4.	Dental Fluorosis
5.	Dentin Sensitivity

Experts

1.	Santos-Pinto, Lourdes: 8 articles (03/2022 - 01/2015)
2.	Jeremias, Fabiano: 5 articles (09/2020 - 01/2015)
3.	Bekes, Katrin: 4 articles (02/2022 - 09/2017)
4.	Cordeiro, Rita de Cássia Loiola: 4 articles (01/2021 - 01/2015)
5.	Sezer, Berkant: 3 articles (05/2022 - 01/2021)
6.	Restrepo, Manuel: 3 articles (03/2022 - 01/2016)
7.	Hickel, Reinhard: 3 articles (01/2022 - 09/2017)
8.	Kühnisch, Jan: 3 articles (01/2022 - 09/2017)
9.	Manton, David John: 3 articles (01/2022 - 11/2017)
10.	Llena, Carmen: 3 articles (01/2021 - 04/2018)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Molar Hypomineralization:

1.	FluoridesIBA 01/01/2016 - "The objective of this study was to investigate the effect of fluoride varnish on remineralization of anterior teeth affected by Molar-Incisor Hypomineralization (MIH) by means of Quantitative Light-Induced Fluorescence- QLF. " 01/01/2016 - "Effect of Fluoride Varnish on Enamel Remineralization in Anterior Teeth with Molar Incisor Hypomineralization." 01/01/2021 - "To evaluate the influence of fluoride varnish (FV) therapies or resin infiltration (RI) to maintain the structural integrity of Molar Incisor Hypomineralization (MIH) -affected teeth. " 11/30/2022 - "To assess the impact of caries, Molar Incisor Hypomineralization (MIH), and fluorosis on the Oral Health-Related Quality of Life (OHRQoL) of schoolchildren aged 8-10 years living in area with different fluoride levels in the drinking water. " 10/15/2022 - "Sulphur dioxide and fluoride co-exposure induce incisor hypomineralization and amelogenin upregulation via YAP/RUNX2 signaling pathway."
2.	Durapatite (Hydroxylapatite)IBA 12/10/2022 - "Remineralization of molar incisor hypomineralization (MIH) with a hydroxyapatite toothpaste: an in-situ study." 10/01/2023 - "Biomimetic hydroxyapatite paste for molar-incisor hypomineralization: A randomized clinical trial." 12/10/2022 - "This randomized, double-blind, crossover, in-situ study, compared the efficacy of toothpastes based on microcrystalline hydroxyapatite (HAP; fluoride-free) or fluoride, in remineralizing molar incisor hypomineralization (MIH). " 10/01/2023 - "The aim of this randomized clinical trial was to evaluate the desensitizing and remineralizing effect of a new zinc-hydroxyapatite-based paste in sites affected by molar-incisor hypomineralization (MIH), by assessing dental sensitivity, tooth wear, and periodontal indexes. "
3.	ToothpastesIBA 12/10/2022 - "Remineralization of molar incisor hypomineralization (MIH) with a hydroxyapatite toothpaste: an in-situ study." 12/10/2022 - "This randomized, double-blind, crossover, in-situ study, compared the efficacy of toothpastes based on microcrystalline hydroxyapatite (HAP; fluoride-free) or fluoride, in remineralizing molar incisor hypomineralization (MIH). "
4.	Caseins (Casein)FDA Link 03/01/2011 - "The use of calcium-phosphate casein on hypomineralized molars (molar incisor hypomineralization, MIH) has been proposed but not clinically investigated. " 02/01/2018 - "Molar incisor hypomineralization treatment with casein phosphopeptide and amorphous calcium phosphate in children." 01/01/2019 - "In vivo Comparative Evaluation of Esthetics after Microabrasion and Microabrasion followed by Casein Phosphopeptide-Amorphous Calcium Fluoride Phosphate on Molar Incisor Hypomineralization-Affected Incisors." 01/01/2022 - "Effect of casein phosphopeptide amorphous calcium fluoride phosphate and calcium glycerophosphate on incisors with molar-incisor hypomineralization: A cross-over, randomized clinical trial." 12/01/2017 - "Comparison of Mineral Density in Molar Incisor Hypomineralization applying fluoride varnishes and casein phosphopeptide-amorphous calcium phosphate."
5.	PhosphopeptidesIBA 02/01/2018 - "Molar incisor hypomineralization treatment with casein phosphopeptide and amorphous calcium phosphate in children." 01/01/2019 - "In vivo Comparative Evaluation of Esthetics after Microabrasion and Microabrasion followed by Casein Phosphopeptide-Amorphous Calcium Fluoride Phosphate on Molar Incisor Hypomineralization-Affected Incisors." 01/01/2022 - "Effect of casein phosphopeptide amorphous calcium fluoride phosphate and calcium glycerophosphate on incisors with molar-incisor hypomineralization: A cross-over, randomized clinical trial." 12/01/2017 - "Comparison of Mineral Density in Molar Incisor Hypomineralization applying fluoride varnishes and casein phosphopeptide-amorphous calcium phosphate." 05/01/2021 - "To compare the efficacy of chewing gum containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and xylitol on salivary characteristics in 8-10 years old children with molar incisor hypomineralization. "
6.	amorphous calcium phosphateIBA 02/01/2018 - "Molar incisor hypomineralization treatment with casein phosphopeptide and amorphous calcium phosphate in children." 12/01/2017 - "Comparison of Mineral Density in Molar Incisor Hypomineralization applying fluoride varnishes and casein phosphopeptide-amorphous calcium phosphate." 05/01/2021 - "To compare the efficacy of chewing gum containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and xylitol on salivary characteristics in 8-10 years old children with molar incisor hypomineralization. " 12/01/2017 - "The aim of the present work was to evaluate and compare variations in mineral density (MD) using laser-induced fluorescence (LF) after applying 5% Sodium Fluoride Varnish (Duraphat®), 5% Sodium Fluoride Varnish with Tricalcium Phosphate (Clinpro®) or Casein phosphopeptide-amorphous calcium phosphate (Recaldent®) on teeth with Molar Incisor Hypomineralization (MIH). "
7.	XylitolIBA 05/01/2021 - "Prathima GS, Narmatha M, Selvabalaji A, et al. Effects of Xylitol and CPP-ACP Chewing Gum on Salivary Properties of Children with Molar Incisor Hypomineralization. " 05/01/2021 - "Effects of Xylitol and CPP-ACP Chewing Gum on Salivary Properties of Children with Molar Incisor Hypomineralization." 05/01/2021 - "To compare the efficacy of chewing gum containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and xylitol on salivary characteristics in 8-10 years old children with molar incisor hypomineralization. "
8.	Chewing Gum (Chewing Gums)IBA 05/01/2021 - "Prathima GS, Narmatha M, Selvabalaji A, et al. Effects of Xylitol and CPP-ACP Chewing Gum on Salivary Properties of Children with Molar Incisor Hypomineralization. " 05/01/2021 - "Effects of Xylitol and CPP-ACP Chewing Gum on Salivary Properties of Children with Molar Incisor Hypomineralization." 05/01/2021 - "To compare the efficacy of chewing gum containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and xylitol on salivary characteristics in 8-10 years old children with molar incisor hypomineralization. "
9.	casein phosphopeptide-amorphous calcium phosphate nanocomplex (Recaldent)IBA 05/01/2021 - "Prathima GS, Narmatha M, Selvabalaji A, et al. Effects of Xylitol and CPP-ACP Chewing Gum on Salivary Properties of Children with Molar Incisor Hypomineralization. " 05/01/2021 - "Effects of Xylitol and CPP-ACP Chewing Gum on Salivary Properties of Children with Molar Incisor Hypomineralization." 05/01/2021 - "To compare the efficacy of chewing gum containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and xylitol on salivary characteristics in 8-10 years old children with molar incisor hypomineralization. "
10.	Dimenhydrinate (DMH)FDA LinkGeneric 11/15/2021 - "Caries experience was significantly higher in children with demarcated molar hypomineralization (DMH) of PFMs and/or PSMs than in the group without. " 05/21/2021 - "Among the most common defects, we recognize Deciduous Molar Hypominerlization (DMH), Hypomineralized Second Primary Molar (HSPM), and Molar Incisor Hypomineralization (MIH). " 03/01/2010 - "At present, knowledge regarding some aetiological factors, like deciduous molar hypomineralization (DMH), is limited. " 11/01/2009 - "For Primary Molar Hypomineralization (DMH) the sensitivity was 72.3%, the specificity 92.8%, the positive likelihood ratio 10.1 and the negative likelihood ratio was 0.30. " 11/01/2009 - "Validity of scoring caries and primary molar hypomineralization (DMH) on intraoral photographs."

Therapies and Procedures

1.	Anesthesia 09/08/2023 - "Effect of photobiomodulation on the efficacy of anesthesia in maxillary permanent molar teeth with molar incisor hypomineralization: A randomized clinical trial." 10/01/2023 - "The current study compares articaine 4% with lidocaine 2% in terms of injection pain and effectiveness of anesthesia when treating permanent mandibular first molars (PMFMs) affected by molar incisor hypomineralization (MIH). "
2.	Low-Level Light Therapy (LLLT) 09/08/2023 - "Effect of photobiomodulation on the efficacy of anesthesia in maxillary permanent molar teeth with molar incisor hypomineralization: A randomized clinical trial." 03/01/2022 - "The aim was to report the use low-level laser therapy (LLLT) in the management of hypersensitivity in an adolescent with molar incisor hypomineralization (MIH) and the impact of LLLT on his oral health-related quality of life (OHRQoL). " 03/01/2022 - "Low-Level Laser Therapy for Management of Hypersensitivity in Molar-Incisor Hypomineralization and Oral Health-Related Quality of Life: Case Report." 11/01/2021 - "Photobiomodulation therapy for hypersensitivity associated with molar-incisor hypomineralization: a case report."
3.	Local Anesthesia 09/01/2018 - "Efficacy of Intraosseous Local Anesthesia for Restorative Procedures in Molar Incisor Hypomineralization-Affected Teeth in Children." 05/01/2022 - "The aim of this prospective study was to compare responses to electrical pulp tests (EPTs) and cold tests among carious teeth with and without molar incisor hypomineralization (MIH) before and after the administration of local anesthesia for caries removal Results: The EPT results of anesthetized carious teeth without MIH were significantly higher than those of carious teeth with MIH (p = 0.011). "
4.	Oral Hygiene (Dental Hygiene) 01/01/2022 - "This study aimed to evaluate the impact of molar incisor hypomineralization (MIH) on oral hygiene and gingival health, and to investigate the relationship between these factors and the severity of MIH. " 01/01/2022 - "Impact of molar incisor hypomineralization on oral hygiene and gingival health in 8-15-years-old children." 02/01/2011 - "Molar-incisor hypomineralization and oral hygiene in 10- to-12-yr-old Swedish children born preterm." 01/01/2020 - "Influence of customized therapy for molar incisor hypomineralization on children's oral hygiene and quality of life." 01/01/2010 - "Specific aims were to analyze behaviour management problems (BMP), dental fear and anxiety (DFA), prevalence of Molar-Incisor Hypomineralization (MIH), oral hygiene, gingival health, and dental caries in PT and full-term C. "
5.	Dental Care 08/06/2018 - "This study assessed the difference in the number of visits made to a dental care clinic and the time spent providing specific dental treatment for children with and without molar incisor hypomineralization (MIH). " 01/01/2021 - "Prevalence and Distribution of Molar Incisor Hypomineralization in children receiving dental care in Caracas Metropolitan Area, Venezuela." 12/13/2018 - "Knowledge, perceptions, and clinical experiences on molar incisor hypomineralization among dental care providers in Hong Kong." 01/01/2012 - "Prevalence of molar-incisor hypomineralization (MIH) in children seeking dental care at the Schools of Dentistry of the University of Buenos Aires (Argentina) and University of la Republica (Uruguay)."