Sperm Proteins

Proteins found in sperm. Sperm-specific proteins have important roles in FERTILIZATION including SPERM MOTILITY and SPERM-OVUM INTERACTIONS. Sperm-specific proteins are also important for early EMBRYO DEVELOPMENT.

Also Known As:

Proteins, Sperm; Proteins, Sperm Specific; Proteins, Sperm Tail; Proteins, Sperm-Specific; Proteins, Spermatozoa; Specific Proteins, Sperm; Tail Proteins, Sperm; Sperm Specific Proteins; Sperm Tail Proteins; Sperm-Specific Proteins; Spermatozoa Proteins

Networked: 54 relevant articles (1 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Seminal Proteins: 8
    - Sperm Proteins: 54

Experts

1.	Agarwal, Ashok: 5 articles (02/2020 - 01/2015)
2.	Sharma, Rakesh: 3 articles (01/2020 - 01/2015)
3.	Barrachina, Ferran: 2 articles (01/2022 - 05/2020)
4.	Jodar, Meritxell: 2 articles (01/2022 - 05/2020)
5.	O'Donnell, Liza: 2 articles (01/2022 - 01/2021)
6.	Oliva, Rafael: 2 articles (01/2022 - 05/2020)
7.	Rebourcet, Diane: 2 articles (01/2022 - 01/2021)
8.	Smith, Lee B: 2 articles (01/2022 - 01/2021)
9.	Soler-Ventura, Ada: 2 articles (01/2022 - 05/2020)
10.	Baskaran, Saradha: 2 articles (02/2020 - 11/2019)

Related Diseases

1.	Infertility (Sterility) 10/01/2023 - "Overt immune response against the sperm proteins leads to idiopathic infertility. " 10/01/2023 - "We expose 31 sperm proteins displaying deviant abundances under infertility, which already were known before to have fertility relevance, including ACTL9, CCIN, CFAP47, CFAP65, CFAP251 (WDR66), DNAH1, and SPEM1. " 08/01/2021 - "Identification of different sperm proteins and diagnosis of DNA damage has positively contributed to the existing pool of knowledge about sperm physiology and molecular anomalies associated with different infertility issues in males. " 11/01/2019 - "Altered expression of sperm proteins may be a major cause of infertility in these men. " 02/01/2003 - "Differential ubiquitination of stallion sperm proteins: possible implications for infertility and reproductive seasonality."
2.	Varicocele 03/01/2016 - "To study the major differences in the distribution of spermatozoa proteins in infertile men with varicocele by comparative proteomics and validation of their level of expression. " 06/01/2014 - "Study of the effect of varicocelectomy on sperm proteins expression in patients with varicocele and poor sperm quality by using two-dimensional gel electrophoresis." 01/01/2021 - "Animals with 3 weeks of varicocele showed a significant (p < 0.05-0.001) decrease in body and sex organ weights, total proteins, sperm characteristics, testosterone concentration, SOD, catalase, and total peroxidase activities. "
3.	Male Infertility (Male Sterility) 11/28/2023 - "Further studies of Cylicins and other sperm proteins in mice may help us to understand some of the factors that contribute to male infertility in humans." 01/01/2021 - "Inclusion criteria: All full-length research articles, systematic reviews, meta-analyses, or abstracts on sperm proteins and male infertility published in the English language in peer-reviewed journals were considered." 01/01/2018 - "The sealtered sperm proteins and the increased spontaneous acrosome reaction rate might account for this unexplained male infertility in the R-ICSI pregnancy patients. " 01/01/2015 - "Understanding the effect of increasing levels of ROS on the differential expression of sperm proteins is important to understand the cellular processes and or/pathways that may be implicated in male infertility. " 01/01/2008 - "Detection of JAM-A in human sperm proteins indicates that its role may be conserved in sperm motility and that JAM-A may be a candidate gene for the analysis of idiopathic sperm motility defects resulting in male subfertility in the human population."
4.	Oligospermia (Oligozoospermia) 01/14/1994 - "Fluorescence polarization studies revealed weaker hydrophobicity around these sperm proteins in oligospermia. " 10/01/2023 - "Numbers of sperm proteins showing at least threefold deviating abundances increased from oligozoospermia (N = 153) and oligoasthenozoospermia (N = 154) to oligoasthenoteratozoospermia (N = 368). "
5.	Herpes Zoster 01/01/2010 - "Identification of human sperm proteins that interact with human zona pellucida3 (ZP3) using yeast two-hybrid system." 09/01/1995 - "Taken together, these findings confirm the involvement of extracted sperm proteins in sperm-zona interactions. " 07/01/2007 - "Two-dimensional gel electrophoresis of ZP fragments with bound sperm proteins showed very reproducibly 24 sperm protein spots to be associated to the zona ghosts after mild plasma membrane solubilization whereas only three protein spots were detected after strong plasma membrane solubilization. " 09/01/1995 - "One droplet of a suspension of spermatozoa was exposed to sperm proteins and then tested for zona binding, while a parallel semen suspension droplet incubated with culture medium served as a control. " 12/01/1994 - "Molecular identities of human sperm proteins that bind human zona pellucida: nature of sperm-zona interaction, tyrosine kinase activity, and involvement of FA-1."

Related Drugs and Biologics

1.	Biomarkers (Surrogate Marker)
2.	Proteins (Proteins, Gene)
3.	Pyroglutamate Hydrolase (5 Oxoprolinase)
4.	Fibronectins (Fibronectin)
5.	Androgens
6.	Antibodies
7.	Antigens
8.	Proteome
9.	Messenger RNA (mRNA)
10.	Protein-Tyrosine Kinases (Tyrosine Kinase)

Related Therapies and Procedures

1.	Contraception (Birth Control)
2.	Immunotherapy
3.	Immunologic Contraception (Immunocontraception)