Dietary Advanced Glycation End Products

Advanced glycation end products (AGEs) present in food. They are absorbed by the GASTROINTESTINAL SYSTEM and contribute to the body's total AGEs. The food BROWNING REACTION, such as occurs during food processing or cooking with high heat (frying, broiling, grilling, roasting, etc.) accelerates the formation of AGEs in food.

Also Known As:

AGE, Dietary; AGEs, Dietary; Advanced Glycation End Product, Dietary; Advanced Glycation End Products, Dietary; Advanced Glycation Endproduct, Dietary; Advanced Glycation Endproducts, Dietary; Dietary AGE; Dietary AGEs; Dietary Advanced Glycation End Product; Dietary Advanced Glycation Endproduct; Dietary Advanced Glycation Endproducts; Dietary Maillard Reaction Product; Dietary Maillard Reaction Products; Maillard Reaction Product, Dietary; Maillard Reaction Products, Dietary

Networked: 179 relevant articles (4 outcomes, 57 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Uribarri, Jaime: 17 articles (03/2022 - 03/2003)
2.	Cai, Weijing: 14 articles (01/2021 - 07/2002)
3.	Vlassara, Helen: 14 articles (05/2015 - 07/2002)
4.	Schalkwijk, Casper G: 8 articles (01/2022 - 07/2015)
5.	Forbes, Josephine M: 7 articles (06/2022 - 03/2010)
6.	Garay-Sevilla, Ma Eugenia: 5 articles (08/2021 - 01/2013)
7.	Peppa, Melpomeni: 5 articles (04/2007 - 03/2003)
8.	Peterson, Lindsay L: 4 articles (12/2021 - 02/2019)
9.	Turner, David P: 4 articles (12/2021 - 02/2019)
10.	Luevano-Contreras, Claudia: 4 articles (12/2018 - 12/2010)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2020 - "The present study helped to define the relationship between dietary AGEs and cancer progression. " 08/01/2022 - "Dietary advanced glycation end products and cancer risk in Japan: From the Takayama study." 10/06/2023 - "Ex vivo fibroblasts from mice fed dietary-AGEs retain an activated phenotype and promoted epithelial migration and invasion of non-transformed immortalized and tumor-derived mammary epithelial cells. " 10/03/2023 - "Dietary advanced glycation end products (AGEs) can play an important role in increasing inflammatory factors and oxidative stress as risk factors for cancers. " 08/01/2022 - "We evaluated the relationship between dietary AGE intake and the incidence of total cancer and site-specific cancers in a population-based prospective study in Japan. "
2.	Cognitive Dysfunction 03/31/2022 - "The goal of this study was to investigate the associations of dietary AGEs (dAGEs) with cognitive decline in older adults. " 01/01/2020 - "This study is the very first to demonstrate that even a short-term dietary advanced glycation end product (dAGEs) intake induced impaired cognitive function in aged ICR mice, and querectin is capable of reversing dAGEs-induced cognitive dysfunction. " 03/31/2022 - "Higher levels of dietary AGE levels in older adults are associated with faster cognitive decline. " 12/01/2021 - "It remains unclear whether dietary advanced glycation end products (dAGEs)-induced cognitive impairment is sex-dependent. " 01/01/2021 - "Dietary advanced glycation end-products (AGEs) are linked to cognitive decline. "
3.	Heart Failure 08/01/2005 - "Age, dietary vitamin K consumption, chronic heart failure, atrial fibrillation, hypertension, smoking and drinking status were found to be factors statistically significant affecting warfarin dosage. " 01/26/1984 - "Recent studies have discriminated between serum levels correlated with therapeutic effectiveness and those accompanied with mild or severe side effects; in addition, it has been clearly shown that the half life of this alkaloid varies from one person to another and with various physiopathologic (age, dietary habits, liver failure, heart failure...) or pharmacologic (drug interactions with enzyme inductors or inhibitors...) factors; these recent advances have led to improved individual adjustment of theophylline dosage using serum concentration assays if needed. "
4.	Hot Flashes 06/01/2023 - "The reduction in dietary AGEs required to achieve a predicted reduction in hot flashes by 1/day was 6933 ku/day for severe and 4366 ku/day for moderate-to-severe hot flashes. " 06/01/2023 - "Changes in dietary AGEs correlated with changes in severe (r = +0.39; p = 0.002) and moderate hot flashes (r = +0.34; p = 0.009) and remained significant after adjustment for changes in energy intake (r = +0.45; p < 0.001; and r = +0.37; p = 0.004, respectively) and changes in body mass index (r = +0.37; p = 0.004; and r = +0.27; p = 0.04, respectively). " 06/01/2023 - "Pearson correlations were used to assess the association between changes in hot flashes and dietary AGEs. " 06/01/2023 - "Dietary advanced glycation end-products and postmenopausal hot flashes: A post-hoc analysis of a 12-week randomized clinical trial." 06/01/2023 - "The reduction in dietary AGEs with a low-fat plant-based diet was associated with a significant reduction in the frequency of severe and moderate-to-severe postmenopausal hot flashes, independent of changes in energy intake and weight loss. "
5.	Liver Failure 01/26/1984 - "Recent studies have discriminated between serum levels correlated with therapeutic effectiveness and those accompanied with mild or severe side effects; in addition, it has been clearly shown that the half life of this alkaloid varies from one person to another and with various physiopathologic (age, dietary habits, liver failure, heart failure...) or pharmacologic (drug interactions with enzyme inductors or inhibitors...) factors; these recent advances have led to improved individual adjustment of theophylline dosage using serum concentration assays if needed. "

Related Drugs and Biologics

1.	Theophylline (Theon)
2.	Enzymes
3.	Alkaloids
4.	Quercetin
5.	Dietary Advanced Glycation End Products
6.	N(6)-carboxymethyllysine (carboxymethyllysine)
7.	Biomarkers (Surrogate Marker)
8.	Insulin (Novolin)
9.	Advanced Glycation End Products
10.	Glucose (Dextrose)

Related Therapies and Procedures

1.	Plant-Based Diet
2.	Renal Dialysis (Hemodialysis)
3.	Mediterranean Diet
4.	Long-Term Care
5.	Glycemic Control