Angiopoietin-Like Protein 1

The first member of the Angiopoietin-like protein family to be discovered. It is considered a key endogenous ANTIANGIOGENIC AGENT which inhibits the proliferation, migration, tube formation, and adhesion of ENDOTHELIAL CELLS.

Also Known As:

Networked: 15 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kuo, Tsang-Chih: 3 articles (01/2017 - 03/2013)
2.	Su, Jen-Liang: 3 articles (01/2017 - 03/2013)
3.	Chen, Haiyan: 2 articles (01/2021 - 12/2017)
4.	Chen, Liubo: 2 articles (01/2021 - 12/2017)
5.	Ding, Kefeng: 2 articles (01/2021 - 12/2017)
6.	Jiang, Kai: 2 articles (01/2021 - 12/2017)
7.	Chang, Yi-Wen: 2 articles (01/2017 - 03/2013)
8.	Chen, Min-Wei: 2 articles (01/2017 - 03/2013)
9.	Chen, Pai-Sheng: 2 articles (01/2017 - 03/2013)
10.	Chiou, Jean: 2 articles (01/2017 - 03/2013)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 01/01/2005 - "In this study we investigated anti-tumour properties of angioarrestin in B16 (F10) melanoma tumour model. " 01/01/2005 - "These data show, to our knowledge for the first time, that angioarrestin can inhibit primary melanoma tumour growth." 01/01/2005 - "Recombinant angioarrestin secreted from mouse melanoma cells inhibits growth of primary tumours."
2.	Neoplasms (Cancer) 01/01/2017 - "Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility." 03/01/2013 - "Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility." 07/29/2005 - "The effects of angioarrestin on tumor cell progression and specific aspects of the angiogenic cascade in in vitro models are further discussed." 01/01/2005 - "Finally, mice were injected subcutaneously with cells that had been transfected with either angioarrestin-encoding vector or empty vector and tumor growth was compared. " 07/01/2002 - "HT1080 cells expressing angioarrestin showed a marked reduction in the number and size of tumor nodules. "
3.	Neoplasm Metastasis (Metastasis) 01/01/2022 - "Angiopoietin-like protein 1 (ANGPTL1) is a member of the ANGPTL family that suppresses angiogenesis, cancer invasion, metastasis, and cancer progression. " 01/07/2021 - "Angiopoietin-like protein 1 (ANGPTL1) has been proved to suppress tumor metastasis in several cancers. " 11/01/2016 - "Angiopoietin-like protein 1 (ANGPTL1) has been shown to act as a tumor suppressor by inhibiting angiogenesis, cancer invasion, and metastasis. " 01/01/2022 - "In the present commentary, we discuss new observations stating that angiopoietin-like protein 1 (ANGPTL1) attenuates cancer metastasis and stemness through Forkhead box O-3a (Foxo3a)-SRY-related HMG-box-2 (Sox2) axis in colorectal cancer (Clin. "
4.	Colorectal Neoplasms (Colorectal Cancer) 02/01/2019 - "Angiopoietin-like protein 1 inhibits epithelial to mesenchymal transition in colorectal cancer cells via suppress Slug expression." 01/01/2022 - "In the present commentary, we discuss new observations stating that angiopoietin-like protein 1 (ANGPTL1) attenuates cancer metastasis and stemness through Forkhead box O-3a (Foxo3a)-SRY-related HMG-box-2 (Sox2) axis in colorectal cancer (Clin. "
5.	Hepatocellular Carcinoma (Hepatoma) 11/01/2020 - "Angiopoietin-like protein 1 (ANGPTL1) may be a novel tumor suppressor in lung, breast, colorectal and hepatocellular carcinoma. " 11/01/2016 - "Angiopoietin-like protein 1 antagonizes MET receptor activity to repress sorafenib resistance and cancer stemness in hepatocellular carcinoma."

Related Drugs and Biologics

1.	Messenger RNA (mRNA)
2.	Angiogenesis Inhibitors
3.	Proteins (Proteins, Gene)
4.	Androgens
5.	Angiopoietin-Like Protein 2
6.	Sorafenib (BAY 43-9006)