Cyclodialysis Clefts

Finding of a separation of the CILIARY BODY in the SCLERAL SPUR region, creating aqueous outflow from the ANTERIOR CHAMBER into suprachoroidal space between the CHOROID and the SCLERA. Persistent cyclodialysis clefts may be associated with OCULAR HYPOTENSION and OPTIC DISC EDEMA.

Also Known As:

Networked: 108 relevant articles (8 outcomes, 11 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Ocular Hypotension
2.	Macular Degeneration (Age-Related Maculopathy)
3.	Wounds and Injuries (Trauma)
4.	Cataract (Cataracts)
5.	Choroidal Effusions

Experts

1.	Zhao, Zhenquan: 3 articles (06/2021 - 01/2014)
2.	Chen, Jiahui: 2 articles (04/2022 - 12/2018)
3.	Jiang, Yongxiang: 2 articles (04/2022 - 12/2018)
4.	Dimitriou, Chrysostomos: 2 articles (03/2022 - 01/2019)
5.	Broc Iturralde, L: 2 articles (03/2022 - 03/2021)
6.	Castillo Capponi, F: 2 articles (03/2022 - 03/2021)
7.	Loscos Arenas, J: 2 articles (03/2022 - 03/2021)
8.	Romera Romero, P: 2 articles (03/2022 - 03/2021)
9.	Falcão-Reis, Fernando: 2 articles (12/2021 - 01/2015)
10.	Wang, Anan: 2 articles (06/2021 - 01/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cyclodialysis Clefts:

1.	ArgonIBA 09/01/2022 - "Intraoperative gonioscopy demonstrated a cyclodialysis cleft and argon endolaser was applied to close the cleft. " 09/01/2022 - "Diagnosis and management of iatrogenic trochar-induced cyclodialysis cleft with intraoperative gonioscopy and argon endolaser." 09/01/2022 - "To report a case of iatrogenic vitrectomy trochar-induced cyclodialysis cleft successfully treated with intraoperative argon endolaser. " 03/08/2022 - "The cyclodialysis cleft was sealed with direct gonioscopic argon laser cyclopexy. " 09/24/2015 - "Considering possible complications and cost of surgical direct cyclopexy, Argon laser can be more beneficial than surgical direct cyclopexy in small-size cyclodialysis cleft below 1.5 clock-hours. "
2.	Retinaldehyde (Retinal)IBA 06/01/1999 - "The present study showed that direct cyclopexy is useful for the treatment of traumatic cyclodialysis cleft associated with ocular hypotony, and that the cyclodialysis should be surgically treated before irreversible retinal folds develop."
3.	HydrogelsIBA 03/01/2008 - "Comparative pathohistological study indicated the evident advantages of a hydrogel implant ensuring the drainage function of the formed cyclodialysis cleft throughout the experiment (5 weeks). " 03/01/2008 - "Complete atresia of the cyclodialysis cleft and cessation of its drainage function might be suggested by week 3. Moreover, hydrogel material has, in our opinion, a less noticeable irritating effect on the adjacent tissues and causes minimum inflammatory and fibroplastic reactions."
4.	Trypan BlueFDA Link 09/01/2019 - "To study the use of trypan blue stained aqueous flow patterns in diagnosing causes of hypotony where cyclodialysis clefts were suspected. " 09/01/2019 - "Use of trypan blue as an aqueous tracer dye to investigate hypotony where cyclodialysis cleft is suspected."
5.	Polymethyl Methacrylate (Sol)IBA 11/01/2011 - "After an unsuccessful direct cyclopexy, phacoemulsification was performed and a normal-sized single-piece polymethyl methacrylate posterior chamber intraocular lens (PMMA PCIOL) was inserted into the ciliary sulcus, with the haptic rotated toward the cyclodialysis cleft. " 07/01/2008 - "One month later, phacoemulsification was performed and a single-piece poly(methyl methacrylate) intraocular lens was inserted into the ciliary sulcus, with the haptic rotated toward the cyclodialysis cleft area. " 10/01/2006 - "intervention: A single piece all-polymethyl methacrylate intraocular lens (PMMA IOL) 13.5 mm in diameter was placed in the ciliary sulcus with the haptics placed in the area of cyclodialysis cleft during cataract surgery and secondary placement of IOL. "
6.	gelatin filmIBA 10/01/1959 - "Evaluation of Gelfilm in cyclodialysis clefts. " 12/01/1958 - "Evaluation of absorbable gelatin film (gelfilm) in cyclodialysis clefts. "
7.	SuspensionsIBA 06/01/1999 - "A human choroidal melanoma cell line (OCM1) was implanted in the choroid of 40 rabbit eyes using three different techniques: transscleral choroidal injection of a cell suspension, injection of a cell suspension in a surgically induced cyclodialysis cleft, and implantation of solid tumor fragments in a surgically induced cyclodialysis cleft. "
8.	SiliconesIBA 12/01/2020 - "A 51-year-old male who had sustained blunt trauma in the left eye two months prior to presentation in the clinics, presented with visual acuity of 20/200, a persistent cyclodialysis cleft with hypotony maculopathy and intraocular pressure (IOP) of 6 mm Hg. A silicone band-buckle was passed 360°; with its anterior edge hugging the insertion of rectus muscles along the 'spiral of Tillaux'. "
9.	Silicone OilsIBA 06/01/2021 - "Comparing the anatomical and functional outcomes of vitrectomy, silicone oil endotamponade without cyclopexy (VEWOC) and with cyclopexy (VEWC) in patients with traumatic cyclodialysis clefts and severe ocular comorbidities. " 06/01/2021 - "COMPARING VITRECTOMY, SILICONE OIL ENDOTAMPONADE WITH/WITHOUT CYCLOPEXY TO TREAT CYCLODIALYSIS CLEFTS WITH SEVERE OCULAR TRAUMA."
10.	Polypropylenes (Polypropylene)IBA 04/20/2006 - "The technique was introduced for suturing a cyclodialysis cleft in which sutures are placed on the corneal limbus to restore the cleft using a long curved needle with 10-0 polypropylene thread, in order to apply tension to the ciliary body which has been relaxed by dialysis. "

Therapies and Procedures

1.	Lasers (Laser) 01/01/2019 - "No patient had received prior laser or surgical treatment for cyclodialysis cleft. " 08/01/2017 - "Traumatic cyclodialysis treated with transscleral ciclodiode laser: Anterior and posterior segment evolution." 03/01/2004 - "Medical, laser, and surgical management of inadvertent cyclodialysis cleft with hypotony." 12/01/1999 - "Treatment of a cyclodialysis cleft by means of ophthalmic laser microendoscope endophotocoagulation." 09/01/1991 - "Laser cyclodialysis cleft consolidation can be repeated easily and safely. "
2.	Light Coagulation 12/01/1999 - "To report on the repair of a cyclodialysis cleft by means of endolaser photocoagulation. " 02/01/1995 - "Direct surgical cyclopexy is a successful treatment for large hypotonus cyclodialysis clefts that are unresponsive to or too large for laser photocoagulation. " 01/01/2017 - "This case demonstrates the specific magnetic resonance appearance of hypotony status caused by a cyclodialysis cleft and the change after laser photocoagulation cyclopexy." 01/01/2017 - "To report the magnetic resonance imaging (MRI) appearance of a man with chronic hypotony caused by unexplained cyclodialysis clefts and the change after laser photocoagulation. " 12/01/1999 - "We describe treatment of a cyclodialysis cleft by means of endolaser photocoagulation with a diode laser. "
3.	Trabeculectomy (Trabeculoplasty) 05/01/2019 - "The aim of this study is to report cyclodialysis cleft creation during Kahook dual blade (KDB) goniotomy. " 05/01/2019 - "Shue A, Levine RM, et al. Cyclodialysis Cleft Associated with Kahook Dual Blade Goniotomy. " 05/01/2019 - "No known reports of cyclodialysis clefts have been published to the authors' knowledge after KDB goniotomy. " 05/01/2019 - "Cyclodialysis Cleft Associated with Kahook Dual Blade Goniotomy." 01/01/2019 - "Full-thickness scleral incisions technique for the treatment of a cyclodialysis cleft following ab interno trabeculotomy."
4.	Scleral Buckling 01/01/2019 - "The result shows that internal direct cyclopexy combined with scleral buckling is an effective treatment for severe traumatic cyclodialysis cleft in OGIS." 12/01/2019 - "These results support the use of scleral buckling with an encircling band as an effective approach for severe hypotony in patients with annular CCD regardless the cyclodialysis cleft extension. " 12/01/2019 - "All patients underwent scleral buckling surgery with an encircling band for annular CCD with cyclodialysis cleft. " 03/01/2006 - "Anterior scleral buckling procedure for cyclodialysis cleft with chronic hypotony." 01/01/2019 - "This study aimed to evaluate the effect of scleral buckling combined with internal cyclopexy on the treatment of severe traumatic cyclodialysis cleft in open globe injuries (OGIS). "
5.	Sutures (Suture) 01/01/2019 - "Combined ab externo cyclopexy with partial-thickness scleral flap dissection and suture reattachment of the ciliary muscle and cryopexy delivered on the partial-thickness scleral bed is safe and effective as primary surgical repair for cyclodialysis cleft." 12/26/2019 - "Fifteen patients successfully underwent continuous mattress suture for repair of cyclodialysis cleft. " 01/01/2019 - "To evaluate outcomes of an ab externo surgical technique combining cyclopexy with partial-thickness scleral flap dissection and suture reattachment of ciliary muscle and cryopexy through partial-scleral bed for cyclodialysis cleft repair. " 09/01/2017 - "Internal cyclopexy was performed using double-armed sutures introduced into the eye through the pars plana opposite to the cyclodialysis cleft and which were laid parallel to limbus. " 08/01/2017 - "Inadvertent cyclodialysis cleft from a malpositioned AIT and resultant hypotony is rare and in this case was successfully treated by direct suture cyclopexy."