Univentricular Heart

05/01/2013 - "The patients with univentricular heart disease with an adverse outcome had a significantly greater 24-hour B-type natriuretic peptide level than those without (P < .05). "
06/01/2012 - "Increase in N-terminus-pro-B-type natriuretic peptide during exercise of patients with univentricular heart after a total cavopulmonary connection."
07/01/2008 - "Increased natriuretic peptide type B level after the second palliative step in children with univentricular hearts with right ventricular morphology but not left ventricular morphology."
01/01/2008 - "To assess plasma B-type natriuretic peptide (BNP) levels in patients with univentricular hearts late after volume unloading by total cavopulmonary connection (TCPC). "
01/01/2008 - "B-type natriuretic peptide levels in patients with functionally univentricular hearts after total cavopulmonary connection."

06/01/1993 - "From these data we would conclude that VVI,R pacing in postoperative univentricular hearts does not result in improved exercise performance and that further study with DDD,R pacing is needed to determine its usefulness in this group of patients."
06/01/1993 - "In this study, the usefulness of both VVI,R and DDD,R pacing are evaluated in the postoperative univentricular heart following the Fontan operation. "

12/01/2010 - "Growth differentiation factor 15 might be helpful in detecting early abnormal function of the Fontan circuit in patients with univentricular hearts. "

01/01/2019 - "The present study aims to identify those miRNAs in patients with univentricular heart (UVH) disease that may be associated with overt heart failure. "
01/01/2019 - "Micro-RNA 150-5p predicts overt heart failure in patients with univentricular hearts."
01/01/2017 - "To test this, we studied the association of heart failure with elevations in specific miRNAs isolated from circulating microvesicles in a cohort of children with univentricular heart disease and heart failure. "
01/01/2020 - "Aim: The present study aims to identify those microRNAs (miRNAs) in patients with univentricular heart (UVH) disease with and without Fontan palliation that may be associated with advanced liver fibrosis/cirrhosis. "
01/01/2020 - "MicroRNA-29b/c-3p Indicate Advanced Liver Fibrosis/Cirrhosis in Univentricular Heart Patients With and Without Fontan Palliation."

02/01/2013 - "The aim of this study was to analyse the midterm results following superior and inferior direct cavopulmonary connections (DCPC) to create a Fontan circulation in patients with functionally univentricular hearts. "
04/01/2012 - "The aim of this study was to analyze the midterm results following direct superior and inferior cavopulmonary connections (DCPC) to create Fontan circulation in patients with functionally univentricular hearts. "

01/01/2017 - "This study demonstrates that miR129-5p is a sensitive and specific biomarker for heart failure in univentricular heart disease independent of ventricular morphology or stage of palliation. "
01/01/2014 - "In this review, we discuss the use of biomarkers in differentiating cardiac from noncardiac disease; predicting the prognosis of patients with heart failure, pulmonary hypertension and dilated cardiomyopathy; diagnosing subclinical cardiac involvement in muscular dystrophy and postchemotherapy cancer patients; detecting acute rejection following heart transplantation; diagnosing Kawasaki disease; aiding the management of postoperative cardiac patients; and managing both common (tetralogy of Fallot) and complex (single-ventricle physiology) congenital heart diseases. "
01/01/2017 - "Plasma microvesicle analysis identifies microRNA 129-5p as a biomarker of heart failure in univentricular heart disease."

12/01/2017 - "The aim of this study was to evaluate if children with functionally univentricular hearts on extracorporeal life support after first-stage palliation surgery have higher requirement of analgesics and sedatives compared with children without extracorporeal life support using a goal-directed nurse-driven analgesia and sedation protocol. "

06/01/2008 - "To study these factors, the stress responses of functionally univentricular hearts were assessed at rest and during low-dose dobutamine stress using cardiovascular magnetic resonance imaging. "

12/01/2017 - "The aim of this study was to evaluate if children with functionally univentricular hearts on extracorporeal life support after first-stage palliation surgery have higher requirement of analgesics and sedatives compared with children without extracorporeal life support using a goal-directed nurse-driven analgesia and sedation protocol. "

01/01/2023 - "The peak oxygen uptake (VO2peak, 37.3 ml/min/kg (25th-75th percentile 31.3-43.8)) varied between specific defects; patients with univentricular hearts had lower VO2peak compared with other CHD. "
10/01/2019 - "Perioperative Assessment of Cerebral Oxygen Metabolism in Infants With Functionally Univentricular Hearts Undergoing the Bidirectional Cavopulmonary Connection."
09/18/2019 - "Introduction Oxygen delivery in patients with functionally univentricular hearts awaiting Norwood palliation depends on a balance between systemic blood flow (Qs) and pulmonary blood flow (Qp). "
12/01/2018 - "The cerebral oxygen metabolism seems to be more affected in cyanotic children with functionally univentricular hearts compared to post-operative acyanotic patients. "
01/03/1997 - "Although chronotropic incompetence was noted in all groups of univentricular heart, marked improvements in both the relationship between heart rate and oxygen uptake and in the ventilatory efficiency were observed after definitive repair. "

11/01/1992 - "The fenestrated Fontan operation has been applied to high-risk patients with univentricular hearts, resulting in improved survival. "
11/01/1991 - "These findings indicate that in spite of an improved chronotropic response to exercise, children with univentricular hearts following the Fontan procedure continue to demonstrate altered hemodynamics which negate potential benefits of VVIR pacing."
12/02/2014 - "The Fontan procedure has improved survival in children with functionally univentricular hearts. "
05/01/2002 - "The Fontan operation has undergone numerous design changes in the last 30 years, which have resulted in an improved morbidity and mortality of patients with a univentricular heart. "
05/01/2002 - "Fontan procedure for univentricular hearts: have changes in design improved outcome?"

05/01/2014 - "Recent significant improvement in surgical management of patients with univentricular palliations has resulted in an increasing number of patients with complex univentricular heart repairs surviving to heart transplantation. "
06/01/2022 - "Our experience shows that extremely high-risk neonates with functionally univentricular hearts who are poor candidates for conventional palliation can be successfully stabilized with concomitant palliation and pulsatile VAD insertion while awaiting cardiac transplantation."
12/08/2021 - "Failures of the Fontan System in Univentricular Hearts and Mortality Risk in Heart Transplantation: A Systematic Review and Meta-Analysis."
12/01/2017 - "The unnatural history of failing univentricular hearts: outcomes up to 25 years after heart transplantation."
11/01/2013 - "In conclusion, the option of heart transplantation should be available and kept in mind for the operated univentricular heart even at pediatric ages, as local peculiarities cause these hearts to fail even earlier than described in the literature."

12/01/1982 - "Studies of the long-term efficacy of palliative operations as well as our experience and that of others with "corrective" operations, which have a relatively short follow-up, do not yet indicate whether presently available surgical procedures can alter the natural history of patients with univentricular heart."
02/01/2012 - "This study aimed to investigate HRV in a cohort of children with univentricular hearts, focusing on the relation between HRV and surgical procedure. "
01/01/2017 - "The most common surgical procedures were staged palliation for functionally univentricular heart (17.6%). "
12/01/2005 - "The functionally univentricular circulation: anatomic substrates and function of the univentricular heart before and after surgical procedures. "
06/01/1984 - "Data are presented from 84 patients (45 males, 39 females), aged 6 days to 25 years (mean 10 years), with univentricular heart who underwent a palliative surgical procedure. "

04/15/2020 - "Because of the absence of one atrioventricular connection hearts with UBC have been classified among functionally univentricular hearts requiring palliative treatment according to the Fontan principle. "
01/01/2020 - "Women with complex functionally univentricular hearts rarely survive into adulthood without corrective or palliative surgery. "
01/01/2020 - "Among live-born children, most preoperative deaths occurred in a palliative care setting and were strongly related to comorbidities and/or univentricular hearts."
09/01/2006 - "After proper discussion with the parents, palliative care is still acceptable for patients with single morphologic right ventricle or other complex single ventricle due to poor survival in the current era. "
05/01/1995 - "Eighty-six children under one year of age with univentricular hearts associated with increased pulmonary flow underwent pulmonary artery banding as the first stage of palliative therapy. "

01/01/2011 - "Percutaneous stent implantation into the interatrial septum in children with univentricular heart and secondary restriction of interatrial communication is a safe and effective method. "
01/01/2011 - "To evaluate efficacy of stent implantation into the interatrial septum in patients with univentricular heart and a secondary restriction of interatrial communication. "
04/01/2017 - "Transcatheter stent-secured Glenn anastomosis, aiming to reduce the invasiveness of palliation in patients with univentricular heart defects, has been reported in large experimental animals. "
02/01/2016 - "For the past two years we have adopted the concept of intraoperative hybrid stenting of RC and arch hypoplasia with large stents in patients with univentricular hearts as standard care procedure. "
02/01/2016 - ""Intraoperative hybrid stenting of recurrent coarctation and arch hypoplasia with large stents in patients with univentricular hearts"."