Hybrid Renal Replacement Therapy

Procedures involving non-continuous blood purification (e.g., dialysis, filtration or perfusion) via vascular access with settings for dialysate and blood flow rates and treatment duration settings hybrid between CRRT TECHNIQUE and IRRT TECHNIQUE.

Also Known As:

Daily Dialysis, Extended; Dialysis, Extended Daily; Dialysis, Sustained Low-Efficiency; Extended Daily Dialyses; Extracorporeal Therapies, Hybrid; Extracorporeal Therapy, Hybrid; Hybrid Extracorporeal Therapies; Hybrid RRTs; RRT, Hybrid; SLED Techniques; SLEDD Techniques; Sustained Low Efficiency Daily Diafiltration; Sustained Low Efficiency Daily Dialysis; Sustained Low Efficiency Dialysis; Sustained Low-Efficiency Dialyses; Therapy, Hybrid Extracorporeal; Extended Daily Dialysis; Hybrid Extracorporeal Therapy; Hybrid RRT; SLED Technique; SLEDD Technique; SLEDDF; Sustained Low-Efficiency Daily Diafiltration; Sustained Low-Efficiency Daily Dialysis; Sustained Low-Efficiency Dialysis

Networked: 123 relevant articles (2 outcomes, 15 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Kielstein, Jan T: 10 articles (01/2016 - 12/2004)
2.	Fiaccadori, Enrico: 8 articles (11/2022 - 12/2004)
3.	Greco, Paolo: 6 articles (11/2022 - 11/2016)
4.	Regolisti, Giuseppe: 6 articles (11/2022 - 11/2016)
5.	Roberts, Jason A: 6 articles (01/2020 - 10/2012)
6.	Welte, Tobias: 5 articles (01/2016 - 01/2008)
7.	Maccari, Caterina: 4 articles (11/2022 - 11/2016)
8.	Maggiore, Umberto: 4 articles (11/2022 - 12/2004)
9.	Wald, Ron: 4 articles (01/2021 - 11/2010)
10.	Parenti, Elisabetta: 4 articles (04/2019 - 12/2004)

Related Diseases

1.	Acute Kidney Injury (Acute Renal Failure) 01/01/2022 - "Comparison of hemodynamic instability among continuous, intermittent and hybrid renal replacement therapy in acute kidney injury: A systematic review of randomized clinical trials." 05/01/2020 - "Sustained low efficiency dialysis (SLED) is an increasingly common treatment option for acute kidney injury (AKI) patients, but there are few studies examining the survival and predictive outcome of this therapy. " 07/27/2012 - "Sustained low efficiency dialysis using a single-pass batch system in acute kidney injury - a randomized interventional trial: the REnal Replacement Therapy Study in Intensive Care Unit PatiEnts." 01/01/2022 - "Sustained low efficiency dialysis (SLED) has been introduced as a mode of renal replacement therapy (RRT) for treating severe cardiac surgery-associated acute kidney injury (CSA-AKI) at some hospitals; SLED is performed using intermittent hemodialysis (IHD) devices but differs from conventional IHD in its duration and intensity. " 01/01/2021 - "Four patients in the HLH group had acute kidney injury (AKI) and two required renal replacement therapy in the form of sustained low efficiency dialysis (SLED). "
2.	Critical Illness (Critically Ill) 01/01/2021 - "We searched the electronic databases for randomized controlled trials (RCTs) comparing different RRT modalities, including continuous RRT, intermittent RRT, hybrid RRT, and peritoneal dialysis (PD), in critically ill patients with AKI through July 26, 2020. " 01/01/2014 - "This trial aimed to compare the dialysis complications occurring during different durations of extended daily dialysis (EDD) sessions in critically ill AKI patients. " 12/20/2012 - "The aim of this study is to evaluate the changes in IAP, GEDVI and EVLWI in critically ill patients receiving slow extended daily dialysis (SLEDD) or continuous venovenous haemofiltration (CVVH) with the intention of net fluid removal. " 01/01/2023 - "Archetypal sustained low-efficiency daily diafiltration (SLEDD-f) for critically ill patients requiring kidney replacement therapy: towards an adequate therapy." 01/01/2023 - "To examine the feasibility, efficacy, and safety of sustained low-efficiency dialysis (SLED) in hemodynamically unstable, critically ill children. "
3.	Snake Bites (Snake Bite) 05/01/2014 - "To investigate the therapeutic efficacy of sustained low-efficiency dialysis (SLED) in severe snakebite patients. " 05/01/2014 - "The report of sustained low-efficiency dialysis (SLED) treatment in fifteen patients of severe snakebite."
4.	Sepsis (Septicemia) 10/01/2012 - "Existing and hybrid extracorporeal therapies are being investigated not only as means to replace lost kidney function, but also to modulate the immune response to sepsis." 03/01/2008 - "Existing and hybrid extracorporeal therapies are being investigated not only as means to replace lost kidney function but also to modulate the immune response to sepsis. " 01/01/2008 - "Sustained low-efficiency daily dialysis with hemofiltration for acute kidney injury in the presence of sepsis." 11/01/2021 - "Population pharmacokinetics and probability of target attainment in patients with sepsis under renal replacement therapy receiving continuous infusion of meropenem: Sustained low-efficiency dialysis and continuous veno-venous haemodialysis." 01/01/2021 - "To assess fosfomycin (FOS) elimination in patients with sepsis and acute kidney injury (AKI) undergoing slow-extended daily dialysis (SLEDD) with the Genius system in a prospective observational study. "
5.	Intracranial Hemorrhages (Intracranial Hemorrhage) 11/01/2013 - "This study aims to compare the effects of hemodynamic parameters and intracranial pressure (ICP) between sustained low-efficiency dialysis (SLED) and continuous veno-venous hemofiltration (CVVH) in dialysis patients with brain hemorrhage. " 11/01/2013 - "The hemodynamic effects during sustained low-efficiency dialysis versus continuous veno-venous hemofiltration for uremic patients with brain hemorrhage: a crossover study."

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Meropenem (Merrem)
3.	Long Noncoding RNA
4.	Interleukin-6 (Interleukin 6)
5.	Metformin (Glucophage)
6.	Citric Acid (Citrate)
7.	Vancomycin
8.	Linezolid (Zyvox)
9.	Daptomycin
10.	Dialysis Solutions

Related Therapies and Procedures

1.	Continuous Renal Replacement Therapy
2.	Renal Dialysis (Hemodialysis)
3.	Therapeutics
4.	Renal Replacement Therapy (Therapies, Renal Replacement)
5.	Peritoneal Dialysis