Secretagogues

02/01/2014 - "We evaluated whether secretagogues can affect QTc interval during cardiac stress test in 20 patients with type 2 diabetes treated with secretagogues. "
02/01/2014 - "Lack of the QTc physiologic decrease during cardiac stress test in patients with type 2 diabetes treated with secretagogues."
08/01/2004 - "Progressive beta-cell failure is a characteristic feature of type 2 diabetes; consequently, beta-cell secretagogues are useful for achieving sufficient glycaemic control. "
02/01/1998 - "This secretagogue may be considered as a novel drug with potential interest for the treatment of NIDDM."
12/01/1986 - "In these NIDDM patients, exposure of pancreatic beta-cells to sustained levels of sulfonylureas induces a reversible state of refractoriness to acute stimulation with sufonylureas but not to another secretagogue.(ABSTRACT TRUNCATED AT 250 WORDS)"

11/01/2018 - "Twelve trials assessed the efficacy of intestinal secretagogues for chronic constipation. "
12/01/2018 - "Efficacy of Secretagogues in Patients With Irritable Bowel Syndrome With Constipation: Systematic Review and Network Meta-analysis."
01/01/2022 - "Using survey data designed to be representative of the United States population, the study identified secretagogues as a key cost factor in drug treatment of constipation. "
01/01/2022 - "The use of secretagogues (10.3% of the cohort) was the best independent predictor of constipation treatment costs. "
01/01/2022 - "Secretagogues have been introduced as new agents for the treatment of constipation. "

07/01/2006 - "These results demonstrate that disruption of or local application of RTX to the celiac ganglion inhibits SP release in the pancreas and reduces the severity of acute secretagogue-induced pancreatitis. "
11/01/2007 - "Most mechanistic studies of pancreatitis in mice employ the secretagogue-induced model. "
04/01/2007 - "In this study, the sensitivity to secretagogue-induced pancreatitis was examined in a mouse line that has an altered acinar cell environment due to the targeted deletion of Mist1. "
11/01/1992 - "In this report I will review the results of studies conducted during the last decade that have employed the diet-induced, secretagogue-induced, and duct obstruction-induced models of experimental pancreatitis to investigate the early events that lead to the development of acute pancreatitis. "
03/01/2013 - "Conversely, P2pal-18S increases the severity of secretagogue-induced pancreatitis. "

07/01/2012 - "Short-acting insulin secretagogues are an option in the subset of fasting diabetic patients who have predominantly post-prandial hyperglycemia."
12/01/2002 - "Control of postprandial hyperglycemia: optimal use of short-acting insulin secretagogues."
10/01/2001 - "Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans."
04/01/1991 - "This positive association between response and degree of hyperglycemia was not found with a nonnutrient secretagogue, 3-isobutyl-1-methylxanthine. "
04/01/1986 - "Rats with NIDD exhibited moderate basal hyperglycemia (less than 2g/l) with defective glucose-induced insulin secretion and preserved or enhanced responsiveness to various non-glucose secretagogues. "

09/01/1989 - "In the present study, we injected MMQ cells into rats to determine whether the tumor cells would become responsive to secretagogues when subsequently propagated in vitro. "
03/01/1988 - "This study documents the establishment of a breeding colony and the characterization of the tumors and their possible secretagogues. "
10/01/2022 - "Primary tumor was not identified by the morphological imaging technologies, but a selective arterial secretagogue injection test suggested its existence in the duodenum or pancreatic head. "
12/01/2015 - "Selective arterial secretagogue injection (SASI) test indicated a tumor within the gastroduodenal arterial zone. "
11/01/2006 - "This method permits determination of mechanisms by which substances released from neoplasms and other sources of vascular endothelial cell secretagogues modulate vascular permeability and likely other pathologic states."