Proctectomy

Surgical resection of the RECTUM.

Also Known As:

Abdomino-Perineal Rectum Excision; Abdomino-Perineal Resection; Abdomino-perineal Excision; Abdominoperineal Excision; Abdominoperineal Rectum Excision; Abdominoperineal Resection; Rectum Excision; Rectum Resection; Abdomino Perineal Rectum Excision; Abdomino Perineal Resection; Abdomino perineal Excision; Abdomino-Perineal Rectum Excisions; Abdomino-Perineal Resections; Abdomino-perineal Excisions; Abdominoperineal Excisions; Abdominoperineal Rectum Excisions; Abdominoperineal Resections; Excision, Abdomino-Perineal Rectum; Excision, Abdomino-perineal; Excision, Abdominoperineal; Excision, Abdominoperineal Rectum; Excision, Rectum; Excisions, Abdomino-Perineal Rectum; Proctectomies; Rectum Excision, Abdomino-Perineal; Rectum Excision, Abdominoperineal; Rectum Excisions; Rectum Resections; Resection, Abdomino-Perineal; Resection, Abdominoperineal; Resection, Rectum; Resections, Abdominoperineal

Networked: 3305 relevant articles (109 outcomes, 336 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 34913
- Digestive System Surgical Procedures: 30
  - Proctectomy: 3305
    - Restorative Proctocolectomy: 2987

Experts

1.	Tanis, Pieter J: 21 articles (11/2022 - 02/2012)
2.	Kalady, Matthew F: 17 articles (10/2022 - 03/2011)
3.	Wexner, Steven D: 17 articles (11/2021 - 11/2003)
4.	Dietz, David W: 16 articles (01/2020 - 06/2004)
5.	Steele, Scott R: 13 articles (11/2022 - 07/2013)
6.	Bemelman, Willem A: 13 articles (01/2022 - 02/2012)
7.	Kim, Nam Kyu: 13 articles (12/2021 - 05/2009)
8.	Tanis, P J: 13 articles (10/2021 - 07/2012)
9.	Stamos, Michael J: 12 articles (10/2017 - 08/2007)
10.	Gorgun, Emre: 11 articles (11/2022 - 06/2016)

Related Diseases

1.	Rectal Neoplasms (Rectal Cancer) 06/01/1999 - "Fueled by a greater understanding of pelvic physiology along with an improved comprehension of rectal cancer spread, we are now able to offer most patients restoration of intestinal continuity following oncologic proctectomy. " 06/01/2023 - "Preoperative radiotherapy has improved outcomes in rectal cancer patients, however, the optimal interval between radiation and proctectomy is unknown. " 12/01/2015 - "Proctectomy with total mesorectal excision (TME) is the gold standard for rectal cancer surgical management, as it offers optimal oncologic results. " 09/01/2010 - "Spiral cuff colostomy with reconstruction after abdominoperineal resection of very low distal rectal cancer offers a surgical option for a selective group of patients with reasonable functional long-term results and an improved quality of life." 03/01/2005 - "Abdominoperineal resection, with iliac colostomy, remains the gold standard treatment for very low-lying rectal cancer, but it alters patients' quality of life. "
2.	Neoplasms (Cancer) 07/15/1995 - "Local tumor control after chemoradiation was seen in 96% (74 out of 77); 2 patients had recurrent disease at the anastomosis site and were treated successfully with abdominoperineal resection. " 01/01/1987 - "The delayed onset of voiding complaints after abdominoperineal resection should prompt a high index of suspicion that a local tumor recurrence may be present." 05/01/2023 - "Abdominoperineal resection with excision of the tumor remains the mainstay of treatment; however, poor patient compliance with permanent colostomy is a major limiting factor of abdominoperineal resection. " 03/01/2013 - "Historically, radical surgery (abdominoperineal resection) has been the mainstay of treatment for both benign and malignant anorectal soft tissue tumors. " 07/01/1999 - "The aim of this study was to compare the safety and efficacy of laparoscopic abdominoperineal resection and open abdominoperineal resection for cancer. "
3.	Wounds and Injuries (Trauma) 03/01/2020 - "Extralevator abdomino-perineal excision (ELAPE) improved oncologic outcomes, but is burdened by important limitations (positioning, wound closure). " 10/01/1991 - "We conclude that mucosal proctectomy results in internal anal sphincter trauma but is associated with long-term sphincter recovery, coupled with a significant improvement in external sphincter capacity, ileal pouch volume, and stool frequency." 11/01/2007 - "If proctectomy is necessary, several strategies such as intersphincteric dissection, avoidance of fecal contamination, and appropriate wound closure, are effective in diminishing the postoperative morbidity of an unhealed perineal wound. " 01/10/2007 - "Our experience shows that careful primary closure of an extended abdominoperineal resection wound is effective and safe. " 09/01/2016 - "The aim of the present study was to determine whether negative pressure therapy applied to closed perineal wounds after ELAPE improved wound healing and compare outcomes to the published literature and outcomes from a historical cohort of patients who had undergone 'standard' abdominoperineal resection (APR) and primary closure of the perineal wounds. "
4.	Carcinoma (Carcinomatosis) 02/01/2009 - "The quality of care of rectal carcinoma patients has improved significantly, as measured by perioperative oncosurgical criteria (abdominoperineal resection rate, total mesorectal excision rate and quality, and proportion of neoadjuvant procedures). " 10/01/1986 - "For the purpose of this study, 232 patients undergoing abdominoperineal resection and 181 subjected to sphincter-saving resections were available for analysis from an NSABP randomized prospective clinical trial designed to ascertain the efficacy of adjuvant therapy in rectal carcinoma (protocol R-01). " 09/01/2012 - "An improvement in oncological outcome has been reported following an extralevator approach to abdominoperineal excision (ELAPE) for low rectal carcinoma. " 10/01/2003 - "Pre- and postoperative adjuvant treatments for locally advanced, operable (R0 resection) rectum carcinoma have led to improved results. " 01/01/1987 - "It is generally not appreciated that the delayed onset of voiding dysfunction after abdominoperineal resection for rectal carcinoma may be the first sign of local pelvic recurrence. "
5.	Adenocarcinoma 07/01/2002 - "Good outcome for patients with adenocarcinoma of the rectum who undergo neoadjuvant external beam radiotherapy and proctectomy is associated with subspecialty training in colon and rectal surgery." 03/01/2005 - "This study was designed to describe and evaluate the efficacy of sutured perineal omentoplasty on perineal wound healing after abdominoperineal resection for adenocarcinoma of the lower rectum. " 10/01/2022 - "AC was associated with improved OS in patients who received neoadjuvant CRT followed by proctectomy for clinical stages II and III rectal adenocarcinoma. " 01/01/2002 - "To determine the efficacy of proctectomy with coloanal anastomosis for adenocarcinoma of the lower third of the rectum, and to compare quality of life after colonal anatomosis with low anterior rectal resection. " 09/01/2023 - "The present study aimed to assess the impact of neoadjuvant therapy on the clinical and pathologic outcomes and overall survival (OS) of patients with stage II-III anal adenocarcinomas after abdominoperineal resection (APR). "

Related Drugs and Biologics

1.	Gentamicins (Gentamicin)
2.	Chewing Gum (Chewing Gums)
3.	Indicators and Reagents (Reagents)
4.	Imatinib Mesylate (Gleevec)
5.	Povidone-Iodine (Betadine)
6.	gentamicin-polymethylmethacrylate bead
7.	Biopex
8.	Collagen
9.	Mucins
10.	Phosphodiesterase 5 Inhibitors

Related Therapies and Procedures

1.	Chemoradiotherapy
2.	Colostomy
3.	Therapeutics
4.	Colectomy
5.	Radiotherapy