Alginic Acid

A polysaccharide and linear copolymer, consisting mainly of beta-1,4-linked D-mannuronic acid and alpha-1,4-linked L-glucuronic acid, that occurs in marine algae such as LAMINARIA, and in BIOFILMS produced by PSEUDOMONAS AERUGINOSA.

Also Known As:

Networked: 66 relevant articles (7 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Wang, Xiong: 4 articles (01/2022 - 05/2017)
2.	Dong, Xiao-Li: 3 articles (01/2022 - 12/2020)
3.	Liu, Xin: 3 articles (01/2022 - 12/2020)
4.	Tang, Qing-Juan: 3 articles (01/2022 - 05/2017)
5.	Du, Zhong-Rui: 2 articles (01/2022 - 12/2020)
6.	Wong, Ka-Hing: 2 articles (01/2022 - 12/2020)
7.	Zhao, Qing: 2 articles (01/2022 - 12/2020)
8.	Liu, Fang: 2 articles (12/2020 - 05/2017)
9.	Kurup, G Muraleedhara: 2 articles (12/2013 - 06/2013)
10.	Sarithakumari, C H: 2 articles (12/2013 - 06/2013)

Related Diseases

1.	Neoplasms (Cancer) 06/01/2023 - "In conclusion, the modification of alginic acid with 4-AP improved its cytotoxic activity against HepG-2 and A-549 cancer cells. " 10/24/2012 - "In vivo near-infrared (NIR) fluorescence imaging and biodistribution examinations showed that the alginic acid nanoparticles could be well-accumulated in the tumor site by the enhanced permeability and retention effect. " 05/01/1988 - "Studies were made of the effects of the embolization and drug releasing of 1-hexylcarbamoyl-5-fluorouracil (HCFU), which has been microencapsulated with alginic acid (HCFUmc), on an unresectable tumor. " 09/14/2023 - "In situ formation of alginic acid-gold nanohybrids for application in cancer photothermal therapy." 09/05/2023 - "In this study, the protective effects of water-soluble alginic acid (WSAA) on the N-terminal of TP5 were investigated by establishing an H22 tumor-bearing mice model and determining thymus, spleen, and liver indices, immune cells activities, TNF-α, IFN-γ, IL-2, and IL-4 levels, and cell cycle distributions. "
2.	Gastroesophageal Reflux (GERD) 10/01/1979 - "This study was designed to evaluate quantitatively the mode of action of alginic acid compound (AAC) in the treatment of patients with symptomatic gastroesophageal reflux. " 10/01/2023 - "Using a societal perspective, we computed the incremental cost-effectiveness ratios (ICERs) in terms of Thai baht (THB) per quality-adjusted life-year (QALY) between a combination of alginic acid plus PPI and standard treatment for GERD. " 12/01/1992 - "An open multicenter study was performed to assess the efficacy and safety of alginic acid in two different dosages in 76 pediatric patients with gastroesophageal reflux confirmed by pH monitoring. " 04/01/1992 - "Alginic acid decreases postprandial upright gastroesophageal reflux. " 10/01/1979 - "The mode of action alginic acid compound in the reduction of gastroesophageal reflux."
3.	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 09/01/2019 - "Recent studies demonstrated a good iron absorption using Feralgine®, a compound of ferrous bysglicinate chelate and alginic acid, oral supplementation with both good compliance rate and efficacy in treating iron deficiency anemia especially due to its high oral bioavailability. "
4.	Infections 08/01/2011 - "Efficacy of a conjugate vaccine containing polymannuronic acid and flagellin against experimental Pseudomonas aeruginosa lung infection in mice." 03/01/1997 - "The natural and semisynthetic carbohydrates scleroglucan, locust bean gum, tamarind gum (glyloid) and its three sulphate derivatives (GP4311, GP4327 and GP4324), glycogen and its two sulphate derivatives (GP4427 and GP4435), alginic acid and dextran sulphate, were investigated for their inhibitory effect on rubella virus (RV) infection of Vero cells. "
5.	Disease Resistance 09/01/2022 - "Individual and combined efficacy of chitooligosaccharides (COS) and alginic acid (AA) at 1 g, 2 g, and 3 g per kg diet was assessed on growth and disease resistance in silver carp (Hypophthalmichthys molitrix) against Edwardsiella ictaluri. "

Related Drugs and Biologics

1.	Antacids
2.	Interleukin-4 (Interleukin 4)
3.	Iron
4.	Interleukin-2 (IL2)
5.	Conjugate Vaccines
6.	Phosphates (Orthophosphate)
7.	Flagellin
8.	Alginates
9.	Polysaccharides (Glycans)
10.	Hydrogels

Related Therapies and Procedures

1.	Therapeutics
2.	Transplantation
3.	Microspheres (Microsphere)
4.	Photothermal Therapy