Calcium Aluminosilicate

Aluminosilicate salts of calcium, the most common of which are CaAl2Si2O8 and Ca2Al2SiO7; a naturally occurring form in CLAY may be used to treat DIARRHEA.

Also Known As:

CASAD; Calcium Aluminosilicate Anti-Diarrheal; Calcium Aluminosilicate Clay; Aluminosilicate Anti-Diarrheal, Calcium; Aluminosilicate Clay, Calcium; Aluminosilicate, Calcium; Anti-Diarrheal, Calcium Aluminosilicate; Calcium Aluminosilicate Anti Diarrheal; Clay, Calcium Aluminosilicate

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Bergeron, Brian E: 1 article (11/2015)
2.	Bortoluzzi, Eduardo A: 1 article (11/2015)
3.	Chen, Ji-hua: 1 article (11/2015)
4.	Cutler, Christopher W: 1 article (11/2015)
5.	Jiao, Kai: 1 article (11/2015)
6.	Niu, Li-na: 1 article (11/2015)
7.	Pashley, David H: 1 article (11/2015)
8.	Primus, Carolyn M: 1 article (11/2015)
9.	Tay, Franklin R: 1 article (11/2015)
10.	Thames, Kyle: 1 article (11/2015)

Related Diseases

1.	Diarrhea 03/01/2015 - "Future CASAD trials will focus on the active treatment of diarrhea." 10/01/2015 - "CASAD is a promising strategy for treatment of MTC-related diarrhea. " 10/01/2015 - "It was hypothesized that CASAD would reduce the severity of diarrhea and improve QOL in MTC patients. " 03/01/2015 - "The rate of any diarrhea among all patients was similar (CASAD arm, 64 % vs. placebo arm, 70 %). " 03/01/2015 - "In evaluable patients, 7 of 43 (16 %) on the CASAD arm compared to 3 of 32 (9 %) on the placebo arm experienced grade 3/4 diarrhea (P = 0.70). "
2.	medullary Thyroid cancer 10/01/2015 - "Efficacy of the Natural Clay, Calcium Aluminosilicate Anti-Diarrheal, in Reducing Medullary Thyroid Cancer-Related Diarrhea and Its Effects on Quality of Life: A Pilot Study."
3.	Colorectal Neoplasms (Colorectal Cancer) 03/01/2015 - "A phase II, randomized, double blind trial of calcium aluminosilicate clay versus placebo for the prevention of diarrhea in patients with metastatic colorectal cancer treated with irinotecan." 03/01/2015 - "We hypothesized that oral administration of CASAD would reduce the rate of grade 3/4 diarrhea associated with irinotecan use for metastatic colorectal cancer (CRC) by adsorbing the SN-38 metabolite. "
4.	Tooth Discoloration 11/30/2015 - "Discoloration-resistant calcium aluminosilicate cement has been formulated to overcome the timely problem of tooth discoloration reported in the clinical application of bismuth oxide-containing hydraulic cements. "
5.	Communicable Diseases (Infectious Diseases) 11/01/2023 - "The Science Popularization and Education Committee of the Academic Divisions of the Chinese Academy of Sciences (CASAD) invited the CAS Institutes of Science and Development (CASISD) and National Science Review (NSR) to organize a roundtable discussion of viral infectious diseases on 11 October 2022. " 11/01/2023 - "Chen Dong () Professor, director of Shanghai Immune Therapy Institute Fu-Sheng Wang () MD., director of the Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases George Fu Gao () Professor, former director-general of Chinese Center for Disease Control and Prevention (China CDC) Zhonghe Zhou (, Chair) Associate director of the Science Popularization and Education Committee of CASAD, professor of CAS Institute of Vertebrate Paleontology and Paleoanthropology and associate editor-in-chief of NSR Yiming Shao () Professor, deputy director of State Key Laboratory for Infectious Disease Control and Prevention, former chief expert on AIDS, China CDC."

Related Drugs and Biologics

1.	Irinotecan (Camptosar)
2.	Calcium Aluminosilicate
3.	Proteins (Proteins, Gene)
4.	Calcium
5.	Antidiarrheals
6.	Clay
7.	bismuth oxide (bismuth trioxide)

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Oral Administration