A family of ENZYMES that, in the presence of calcium ion, converts ARGININE to CITRULLINE in proteins. There are five PAD isotypes in mammals. In humans: they include PAD1, 2, 3, 4 and 6. They are encoded by five paralogous genes named PADI and clustered on human chromosome 1.
Also Known As:
Peptidylarginine Deiminase; Peptidylarginine Deiminases; Protein-Arginine Deiminase; Protein-L-Arginine Iminohydrolase; Protein-L-Arginine Iminohydrolases; Deiminase, Peptidylarginine; Deiminase, Protein-Arginine; Deiminases, Peptidylarginine; Deiminases, Protein-Arginine; Iminohydrolase, Protein-L-Arginine; Iminohydrolases, Protein-L-Arginine; Protein Arginine Deiminase; Protein Arginine Deiminases; Protein L Arginine Iminohydrolase; Protein L Arginine Iminohydrolases