A family of calcium-independent cell adhesion molecules of the immunoglobulin superfamily. They are expressed by most cell types and mediate both homotypic and heterotypic cell-cell adhesion. Nectins function in a variety of morphogenetic and developmental processes that include organogenesis of the eye, ear, tooth, and cerebral cortex; they also play roles in viral infection and cell proliferation.
Also Known As:
CD111 Antigen; CD112 Antigen; CD113 Antigen; Herpesvirus Entry Mediator C; HevC Protein; Human Poliovirus Receptor Related 1; Nectin; Nectin-1; Nectin-1delta; Nectin-2; Nectin-2alpha; Nectin-2delta; Nectin-2gamma; Nectin-3; Nectin1delta; PVRL1; Poliovirus Receptor-Related Protein 1; Prr1 Protein; Antigen, CD111; Antigen, CD112; Antigen, CD113; Nectin 1; Nectin 1delta; Nectin 2; Nectin 2alpha; Nectin 2delta; Nectin 2gamma; Nectin 3; Poliovirus Receptor Related Protein 1